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CMTR2 Knockout Cell Lines

Gene: CMTR2

Official Full Name: cap methyltransferase 2provided by HGNC

Gene Summary: Enables mRNA (nucleoside-2'-O-)-methyltransferase activity. Involved in 7-methylguanosine mRNA capping. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18644 CMTR2 Knockout cell line (HeLa) Human CMTR2 1:3~1:6 Negative Online Inquiry
KO18645 CMTR2 Knockout cell line (HCT 116) Human CMTR2 1:2~1:4 Negative Online Inquiry
KO18646 CMTR2 Knockout cell line (HEK293) Human CMTR2 1:3~1:6 Negative Online Inquiry
KO18647 CMTR2 Knockout cell line (A549) Human CMTR2 1:3~1:4 Negative Online Inquiry

Background

CMTR2 Gene Knockout Cell Lines are specialized cellular models in which the CMTR2 gene has been systematically disrupted or "knocked out," resulting in a loss of function that allows researchers to investigate the gene's biological role, mechanisms of action, and implications in various physiological and pathological contexts. CMTR2 (Cap methyltransferase 2) has been implicated in critical cellular functions, including mRNA processing and translation regulation, making its study essential for understanding gene expression control.

These cell lines function as powerful tools to analyze the consequences of CMTR2 loss on cellular processes. Researchers can utilize these lines to assess impacts on mRNA stability, translation efficiency, and downstream signaling pathways, providing insights into the gene's influence on cell proliferation, differentiation, and response to stress. By observing the phenotypic and molecular changes elicited by the knockout, scientists can draw connections between CMTR2 function and broader cellular functions, particularly in the context of diseases such as cancer or neurodegenerative disorders where gene expression regulation is pivotal.

One of the key advantages of using CMTR2 Gene Knockout Cell Lines is their ability to provide a clear and reliable model for functional genomics studies. Unlike traditional gene silencing techniques such as RNA interference, which can yield variable results depending on off-target effects or incomplete knockdown, CRISPR/Cas9-mediated knockout ensures a permanent and precise disruption of the target gene. This specificity facilitates clearer interpretations of experimental outcomes and bolsters the reproducibility of research findings.

Researchers and clinicians alike can find substantial value in utilizing these cell lines, as they offer a unique platform for drug discovery, validation of therapeutic targets, and the development of personalized medicine approaches. Understanding the role of CMTR2 could lead to novel insights into therapeutic interventions for diseases linked to its dysregulation.

At our company, we pride ourselves on our expertise in developing cutting-edge biological research products. By providing high-quality CMTR2 Gene Knockout Cell Lines, we equip scientists with invaluable resources that advance their research and contribute significantly to the scientific community’s understanding of critical biological processes.

Please note that all services are for research use only. Not intended for any clinical use.

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