Gene: CHST13
Official Full Name: carbohydrate sulfotransferase 13provided by HGNC
Gene Summary: The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to the C4 hydroxyl of beta-1,4-linked N-acetylgalactosamine (GalNAc) flanked by glucuronic acid residue in chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. [provided by RefSeq, Aug 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18697 | CHST13 Knockout cell line (HeLa) | Human | CHST13 | 1:3~1:6 | Negative | Online Inquiry |
CHST13 Gene Knockout Cell Lines represent a cutting-edge tool in molecular biology that provides essential insight into the function of the carbohydrate sulfotransferase 13 (CHST13) gene. These cell lines have been meticulously developed by knocking out the CHST13 gene, thereby allowing researchers to probe into the implications of its absence on cellular functions, signaling pathways, and overall cell behavior. By studying these knockout models, scientists can elucidate the gene's role in various biological processes, including the sulfation of glycosaminoglycans, which is crucial for normal cellular interactions and signaling.
The primary mechanism behind the functionality of CHST13 Gene Knockout Cell Lines lies in their ability to mimic disease states and identify potential therapeutic targets. Without the CHST13 gene's activity, researchers can observe phenotypic changes, alterations in cellular adhesion properties, and variations in response to external stimuli. This makes these knockout lines invaluable in dissecting the molecular underpinnings of various conditions linked to glycosaminoglycan dysregulation, such as developmental disorders and certain cancers.
Scientifically, CHST13 Gene Knockout Cell Lines offer significant applications in research and clinical settings. They can be employed in drug discovery processes, allowing for the identification of compounds that may restore normal function or mitigate disease symptoms. Moreover, these cell lines facilitate the exploration of gene therapy techniques, providing a foundational platform for developing interventions targeting sulfation-related pathways.
One of the distinct advantages of utilizing CHST13 Gene Knockout Cell Lines is their specificity and precision. Unlike conventional cell lines, which may exhibit variable gene expression, these knockout models provide a more consistent and reproducible experimental framework. This specificity enhances the reliability of research findings, making them more robust and applicable to clinical scenarios.
For researchers, clinicians, and biotechnology companies interested in innovative solutions for investigating gene function, the CHST13 Gene Knockout Cell Lines present an invaluable resource that accelerates understanding and fosters breakthroughs. Our company prides itself on delivering high-quality biological products backed by years of expertise in cell line development and molecular genetics. By choosing our cell lines, you gain access to a well-characterized model that can advance your research and clinical applications in significant ways.
Please note that all services are for research use only. Not intended for any clinical use.
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