Gene: CHN2
Official Full Name: chimerin 2provided by HGNC
Gene Summary: This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that contains a phorbol-ester/diacylglycerol (DAG)-type zinc finger, a Rho-GAP domain, and an SH2 domain. The encoded protein translocates from the cytosol to the Golgi apparatus membrane upon binding by diacylglycerol (DAG). Activity of this protein is important in cell proliferation and migration, and expression changes in this gene have been detected in cancers. A mutation in this gene has also been associated with schizophrenia in men. Alternative transcript splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, May 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO38555 | CHN2 Knockout cell line (HeLa) | Human | CHN2 | 1:3~1:6 | Negative | Online Inquiry |
KO38556 | CHN2 Knockout cell line (HCT 116) | Human | CHN2 | 1:2~1:4 | Negative | Online Inquiry |
KO38557 | CHN2 Knockout cell line (HEK293) | Human | CHN2 | 1:3~1:6 | Negative | Online Inquiry |
CHN2 Gene Knockout Cell Lines are specially engineered cellular models where the CHN2 gene, implicated in crucial metabolic processes and neurodevelopment, has been selectively disrupted. This product serves as a powerful tool for researchers investigating the role of the CHN2 gene in biological functions and disease mechanisms, enabling in-depth functional studies of this important genetic target.
The key functionality of CHN2 Gene Knockout Cell Lines lies in their ability to mimic disease states by providing a platform to elucidate the gene's role in cellular processes. With the knockout of the CHN2 gene, researchers can observe alterations in metabolic pathways, cellular signaling, and phenotypic changes that are critical in understanding its significance in health and disease. This enables a variety of applications, such as drug discovery, molecular biology research, and genetic studies, providing insight into potential therapeutic targets.
Scientifically, these cell lines are of paramount importance because they allow for precise investigations into the physiology and pathophysiology associated with CHN2 dysfunction. In clinical settings, findings derived from such models can lead to breakthroughs in understanding diseases linked to CHN2 anomalies, ultimately facilitating the development of targeted therapies.
Compared to traditional cell lines or other knockout models, CHN2 Gene Knockout Cell Lines offer enhanced specificity and reliability, ensuring that researchers can draw meaningful conclusions without the confounding variables often present in less sophisticated models. Moreover, these lines are developed using cutting-edge gene editing technologies, ensuring high efficiency and reproducibility.
For researchers and clinicians, the value of the CHN2 Gene Knockout Cell Lines is evident in their ability to provide insights that can catalyze advances in biomedical research and therapeutic interventions. Their design allows for innovative experimental setups, enabling reliable analysis of the gene's impact in a controlled environment.
At [Company Name], we pride ourselves on our expertise in developing high-quality biological products that support groundbreaking research. Our CHN2 Gene Knockout Cell Lines exemplify our commitment to providing essential tools for scientific discovery, ensuring our users stay at the forefront of genetic research.
Please note that all services are for research use only. Not intended for any clinical use.
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