Gene: CHDH
Official Full Name: choline dehydrogenaseprovided by HGNC
Gene Summary: The protein encoded by this gene is a choline dehydrogenase that localizes to the mitochondrion. Variations in this gene can affect susceptibility to choline deficiency. A few transcript variants have been found for this gene, but the full-length nature of only one has been characterized to date. [provided by RefSeq, Dec 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18731 | CHDH Knockout cell line (HeLa) | Human | CHDH | 1:3~1:6 | Negative | Online Inquiry |
KO18732 | CHDH Knockout cell line (HCT 116) | Human | CHDH | 1:2~1:4 | Negative | Online Inquiry |
KO18733 | CHDH Knockout cell line (HEK293) | Human | CHDH | 1:3~1:6 | Negative | Online Inquiry |
KO18734 | CHDH Knockout cell line (A549) | Human | CHDH | 1:3~1:4 | Negative | Online Inquiry |
CHDH Gene Knockout Cell Lines represent a cutting-edge tool for researchers investigating the functional roles of the CHDH gene within cellular and molecular contexts. These cell lines are specifically engineered to exhibit a complete disruption of the CHDH gene, allowing for the study of its biological implications, mechanisms of action, and interactions with various metabolic pathways. By utilizing CRISPR-Cas9 technology or similar gene-editing approaches, these knockout cell lines facilitate the precise alteration of the genome, thereby enabling investigators to discern gene functions through loss-of-function studies.
The primary function of CHDH Gene Knockout Cell Lines is to provide a reliable model for examining the downstream effects of CHDH gene deletion on cellular behavior, such as proliferation, apoptosis, and metabolic activity. Researchers can utilize these models to elucidate the role of CHDH in processes such as neurotransmitter synthesis and oxidative stress response, thereby advancing our understanding of related diseases, including neurodegenerative disorders and metabolic syndromes.
The scientific importance of these cell lines extends to both basic and translational research. In laboratory settings, they serve as invaluable tools for screening potential therapeutic compounds, understanding gene-environment interactions, and validating the biological relevance of metabolic pathways involving CHDH. Clinically, insights gained from these models could inform the development of targeted interventions that restore normal gene function or mitigate the effects of gene knockout scenarios in disease contexts.
What sets CHDH Gene Knockout Cell Lines apart from alternative models is their reliability and specificity. Unlike other models that may exhibit partial knockout or compensate through alternative pathways, these cell lines ensure a thorough and consistent loss of CHDH gene expression, yielding unambiguous experimental results. Additionally, they are available in various backgrounds, allowing for customization to fit specific research needs.
For researchers and clinicians, CHDH Gene Knockout Cell Lines offer a powerful asset for elucidating the complexities of gene function in human health and disease. By providing a platform for rigorous investigation, they support advancements in molecular biology, pharmacology, and gene therapy.
Our company, with a robust background in genetic engineering and a commitment to advancing scientific knowledge, dedicates itself to delivering high-quality biological products that empower researchers and clinicians alike. We continuously strive to innovate and provide exceptional tools, ensuring that our customers have access to the latest advancements in the field.
Please note that all services are for research use only. Not intended for any clinical use.
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