Gene: CHD5
Official Full Name: chromodomain helicase DNA binding protein 5provided by HGNC
Gene Summary: This gene encodes a member of the chromodomain helicase DNA-binding protein family. Members of this family are characterized by a chromodomain, a helicase ATP-binding domain and an additional functional domain. This gene encodes a neuron-specific protein that may function in chromatin remodeling and gene transcription. This gene is a potential tumor suppressor gene that may play a role in the development of neuroblastoma. [provided by RefSeq, Feb 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28429 | CHD5 Knockout cell line (HCT 116) | Human | CHD5 | 1:2~1:4 | Negative | Online Inquiry |
CHD5 Gene Knockout Cell Lines are advanced biological tools designed to investigate the functional role of the CHD5 gene in cellular processes. The CHD5 gene, known for its involvement in chromatin remodeling and transcription regulation, plays a crucial role in various biological pathways linked to cancer and neurodevelopmental disorders. By creating knockout cell lines, researchers can effectively disable the expression of CHD5, thereby elucidating its specific contributions to cellular behavior and disease mechanisms.
These cell lines utilize the CRISPR-Cas9 gene-editing technology, ensuring precise and efficient gene disruption. The mechanism relies on the formation of double-strand breaks at specific locations within the DNA, which, when repaired, lead to loss-of-function mutations in the CHD5 gene. This functionality allows researchers to study the phenotypic alterations and molecular responses associated with the absence of CHD5, making it an invaluable asset in cancer research, developmental biology, and therapeutic investigations.
The scientific importance of CHD5 Gene Knockout Cell Lines is underscored by their application in high-throughput screenings, validation of drug targets, and personalized medicine research. These cell lines enable the exploration of gene function in a controlled environment, allowing for detailed analyses of cellular pathways and the discovery of novel therapeutic strategies.
What sets our CHD5 Gene Knockout Cell Lines apart from alternative models is their rigorous validation and optimized protocols for maintenance and transfection, ensuring reliability and reproducibility in experimental outcomes. Moreover, they come with extensive support materials, including detailed guidelines for experimental design, enhancing user confidence and success.
Investing in CHD5 Gene Knockout Cell Lines empowers researchers and clinicians to gain deeper insights into gene function and its implications in health and disease. These models facilitate groundbreaking discoveries that could pave the way for innovative treatment approaches. Our company boasts a strong background in molecular biology and genetics, with a commitment to providing high-quality research tools tailored to the evolving needs of the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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