Gene: CGN
Official Full Name: cingulinprovided by HGNC
Gene Summary: Enables cadherin binding activity. Predicted to be involved in microtubule cytoskeleton organization. Predicted to act upstream of or within bicellular tight junction assembly and epithelial cell morphogenesis. Located in bicellular tight junction and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18759 | CGN Knockout cell line (HeLa) | Human | CGN | 1:3~1:6 | Negative | Online Inquiry |
KO18760 | CGN Knockout cell line (HCT 116) | Human | CGN | 1:2~1:4 | Negative | Online Inquiry |
KO18761 | CGN Knockout cell line (HEK293) | Human | CGN | 1:3~1:6 | Negative | Online Inquiry |
KO18762 | CGN Knockout cell line (A549) | Human | CGN | 1:3~1:4 | Negative | Online Inquiry |
CGN Gene Knockout Cell Lines are genetically-engineered cell lines designed to facilitate the study of specific gene functions through the complete inactivation or "knockout" of target genes. By utilizing cutting-edge CRISPR/Cas9 technology, these cell lines enable researchers to precisely disrupt gene expression, yielding invaluable insights into gene function, protein interactions, and cellular processes. The mechanisms behind these knockout lines hinge on the introduction of double-strand breaks in the DNA, followed by an error-prone repair mechanism that leads to the deletion or insertion of nucleotides, effectively rendering the gene nonfunctional.
The scientific importance of CGN Gene Knockout Cell Lines cannot be overstated; they serve as essential tools for elucidating the roles of genes in various biological contexts, including disease models, drug discovery, and developmental biology. Their applications in clinical settings and basic research drive advancements in personalized medicine, cancer research, and regenerative medicine, enabling scientists to develop therapies that target genetic disorders and improve patient outcomes.
Compared to traditional gene silencing approaches such as RNA interference (RNAi), CGN Gene Knockout Cell Lines offer significant advantages, including greater specificity and permanence in gene disruption. This allows for a more robust investigation of gene function and the resulting phenotypic changes, promoting reproducibility and clarity of experimental outcomes. Additionally, the ability to generate multiple knockout lines targeting various genes simultaneously accelerates research timelines and enhances experimental flexibility.
For researchers and clinicians looking to deepen their understanding of genetics and develop innovative therapeutic strategies, CGN Gene Knockout Cell Lines provide a powerful platform for exploration. The precision and versatility of these cell lines make them a cornerstone in modern biological research. At our company, we pride ourselves on our expertise in delivering high-quality, reliable biological products like CGN Gene Knockout Cell Lines, empowering scientists to push the boundaries of discovery and clinical application.
Please note that all services are for research use only. Not intended for any clinical use.
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