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CFAP157 Knockout Cell Lines

Gene: CFAP157

Official Full Name: cilia and flagella associated protein 157provided by HGNC

Gene Summary: Predicted to enable microtubule binding activity. Predicted to be involved in sperm axoneme assembly. Located in cytosol; intracellular membrane-bounded organelle; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18771 CFAP157 Knockout cell line (HeLa) Human CFAP157 1:3~1:6 Negative Online Inquiry
KO18772 CFAP157 Knockout cell line (HCT 116) Human CFAP157 1:2~1:4 Negative Online Inquiry
KO18773 CFAP157 Knockout cell line (HEK293) Human CFAP157 1:3~1:6 Negative Online Inquiry
KO18774 CFAP157 Knockout cell line (A549) Human CFAP157 1:3~1:4 Negative Online Inquiry

Background

CFAP157 Gene Knockout Cell Lines are genetically engineered cell lines designed to facilitate the study of the CFAP157 gene, which is implicated in several critical biological processes, including ciliary function and various pathologies. These knockout cell lines have been precisely altered using CRISPR-Cas9 technology, allowing for the complete disruption of the CFAP157 gene, providing researchers with invaluable tools to explore its role in health and disease.

The primary function of CFAP157 knockout cell lines is to enable the investigation of the gene's contribution to cellular mechanisms and phenotypes associated with ciliary defects. By observing the cellular behavior of these knockout lines in comparison to wild-type counterparts, researchers can elucidate pathways affected by CFAP157 loss, facilitating insights into conditions such as primary ciliary dyskinesia and related ciliopathies. Furthermore, these cell lines create a platform for examining the cellular response to various treatments and environmental factors, thereby enhancing our understanding of therapeutic options in clinical applications.

The scientific importance of CFAP157 knockout cell lines lies not only in their ability to mimic disease states but also in their utility for drug screening, gene therapy studies, and elucidating gene function. Compared to traditional methods, the CRISPR-based knockout strategy allows for more targeted and efficient gene modification, leading to higher specificity and fewer off-target effects.

The unique advantages of our CFAP157 knockout cell lines include robust validation, consistent performance, and a genetic background that supports high cell viability and transfection efficiency, making them superior choices over traditional cell models or alternative gene targeting methods. Their precise engineering and rigorous quality control set them apart, ensuring that researchers can trust the reliability of their experimental results.

Choosing CFAP157 Gene Knockout Cell Lines from our company means investing in your research with tools that are backed by our extensive experience in genetic engineering and cell biology. Our commitment to providing high-quality, scientifically validated products ensures that researchers and clinicians can advance their investigations with confidence, accelerating discoveries that could lead to better therapeutic strategies.

Please note that all services are for research use only. Not intended for any clinical use.

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