Gene: CETN2
Official Full Name: centrin 2provided by HGNC
Gene Summary: Caltractin belongs to a family of calcium-binding proteins and is a structural component of the centrosome. The high level of conservation from algae to humans and its association with the centrosome suggested that caltractin plays a fundamental role in the structure and function of the microtubule-organizing center, possibly required for the proper duplication and segregation of the centrosome. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO38577 | CETN2 Knockout cell line (HeLa) | Human | CETN2 | 1:3~1:6 | Negative | Online Inquiry |
KO38578 | CETN2 Knockout cell line (HCT 116) | Human | CETN2 | 1:2~1:4 | Negative | Online Inquiry |
KO38579 | CETN2 Knockout cell line (HEK293) | Human | CETN2 | 1:3~1:6 | Negative | Online Inquiry |
KO38580 | CETN2 Knockout cell line (A549) | Human | CETN2 | 1:3~1:4 | Negative | Online Inquiry |
CETN2 Gene Knockout Cell Lines are specifically engineered cellular models in which the CETN2 gene, known for its role in cytoskeletal organization and cellular signaling, has been functionally disrupted. Utilizing advanced CRISPR/Cas9 gene-editing technologies, these cell lines facilitate precise modifications that allow researchers to investigate the biological repercussions of CETN2 deficiency. The knockout of this gene is pivotal, as it provides insights into the cellular machinery that regulates critical processes such as cell division, migration, and response to stress.
The primary function of these cell lines is to serve as powerful tools for elucidating the pathways affected by CETN2. Researchers can utilize them to assess changes in gene expression, protein interactions, and cellular behaviors in response to the absence of CETN2. Such investigations are crucial in understanding various pathological conditions, including cancer, where cytoskeletal dynamics and cellular signaling pathways play significant roles.
The scientific importance of CETN2 Gene Knockout Cell Lines extends to both basic research and clinical applications. They are invaluable for drug discovery, allowing the identification of potential therapeutic targets and the screening of compounds that could remediate defects caused by CETN2 loss. Furthermore, these cell lines can aid in studying developmental biology, neurobiology, and immune responses, making them versatile tools across multiple fields of research.
Among their competitive advantages, CETN2 Gene Knockout Cell Lines offer unparalleled specificity and reproducibility, which are essential for producing reliable and interpretable data. Compared to traditional knockdown approaches, the knockout method provides a complete loss-of-function model, representing a more accurate depiction of the gene's role in cellular processes. This precision enhances the reliability of experimental outcomes, thereby facilitating more robust findings.
For researchers and clinicians, the value of CETN2 Gene Knockout Cell Lines lies not only in their functionality but also in the depth of insights they provide into complex biological systems. By unraveling the roles of critical genes like CETN2, these models contribute significantly to our understanding of health and disease.
Our company prides itself on its expertise in developing high-quality biological products and innovative research tools. With a commitment to advancing scientific inquiry, we ensure that our CETN2 Gene Knockout Cell Lines meet the highest standards of reliability and performance, empowering researchers to make transformative discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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