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CERS6 Knockout Cell Lines

Gene: CERS6

Official Full Name: ceramide synthase 6provided by HGNC

Gene Summary: Enables sphingosine N-acyltransferase activity. Involved in ceramide biosynthetic process. Located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO07671 CERS6 Knockout cell line (HeLa) Human CERS6 1:3~1:6 Negative Online Inquiry
KO07672 CERS6 Knockout cell line (HCT 116) Human CERS6 1:2~1:4 Negative Online Inquiry
KO07673 CERS6 Knockout cell line (HEK293) Human CERS6 1:3~1:6 Negative Online Inquiry
KO07674 CERS6 Knockout cell line (A549) Human CERS6 1:3~1:4 Negative Online Inquiry

Background

CERS6 Gene Knockout Cell Lines are specialized cellular models created using advanced gene editing techniques to specifically disrupt the Ceramide Synthase 6 (CERS6) gene. This product represents a critical resource for researchers exploring the role of sphingolipids in various biological processes, such as cell signaling, metabolism, and apoptosis. By knocking out the CERS6 gene, these cell lines facilitate the investigation into how altered sphingolipid metabolism influences cellular behavior and can contribute to various disease states, including cancer and metabolic disorders.

The key mechanism of CERS6 gene knockout involves targeted genome editing, typically utilizing CRISPR-Cas9 technology, which has revolutionized molecular biology by allowing precise modifications to the genome. This enables scientists to assess the phenotypic consequences of CERS6 deficiency, offering insights into its functional roles in lipid metabolism and how these processes are disrupted in pathological conditions.

The scientific importance of CERS6 Gene Knockout Cell Lines extends to both research and clinical applications. In academic and pharmaceutical research, these cell lines can be employed in drug discovery processes, helping to evaluate novel therapeutic targets. Additionally, they provide invaluable tools for studying the intricate pathways involved in lipid metabolism and their implications in diseases, thereby advancing our understanding of potential interventions.

Compared to traditional cell lines, CERS6 knockout models provide the advantage of a more relevant biological context for studying genetic functions and disease mechanisms. They are tailored for high reproducibility and consistent performance, allowing for more reliable data acquisition across experiments. Furthermore, researchers can utilize these lines to develop personalized medicine approaches focused on sphingolipid-targeted therapies.

For researchers, clinicians, and industry professionals, the CERS6 Gene Knockout Cell Lines are an essential addition to their toolkit, enabling significant advancements in understanding complex biological systems and addressing unmet medical needs. Our company specializes in delivering high-quality biological products backed by extensive expertise in gene editing technologies and a commitment to supporting innovative research. By choosing our CERS6 knockout models, you are investing in reliable, cutting-edge tools that will enhance your research outcomes and contribute to scientific advancement.

Please note that all services are for research use only. Not intended for any clinical use.

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