Gene: CCDC88B
Official Full Name: coiled-coil domain containing 88Bprovided by HGNC
Gene Summary: This gene encodes a member of the hook-related protein family. Members of this family are characterized by an N-terminal potential microtubule binding domain, a central coiled-coiled and a C-terminal Hook-related domain. The encoded protein may be involved in linking organelles to microtubules. [provided by RefSeq, Oct 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18988 | CCDC88B Knockout cell line (HeLa) | Human | CCDC88B | 1:3~1:6 | Negative | Online Inquiry |
KO18989 | CCDC88B Knockout cell line (HCT 116) | Human | CCDC88B | 1:2~1:4 | Negative | Online Inquiry |
KO18990 | CCDC88B Knockout cell line (A549) | Human | CCDC88B | 1:3~1:4 | Negative | Online Inquiry |
CCDC88B Gene Knockout Cell Lines are engineered cell models that have been precisely modified to disrupt the expression of the CCDC88B gene, a critical component associated with various cellular processes, including cytoskeletal dynamics and signal transduction pathways. The knockout of this gene allows researchers to investigate its functional roles and interactions in disease models, particularly in the context of cancer and neurodegeneration.
The primary mechanism behind these knockout cell lines involves the use of CRISPR-Cas9 technology, which enables targeted alterations in the genome with high specificity and efficiency. By creating a null allele of the CCDC88B gene, these cell lines provide an invaluable tool for elucidating the gene’s contributions to biological pathways and disease phenotypes. Furthermore, they facilitate the exploration of compensatory mechanisms by other genes, thereby enriching the understanding of gene networks involved in cellular behavior.
The scientific importance of CCDC88B Gene Knockout Cell Lines lies in their applications in both basic and translational research, providing insights into the underlying mechanisms of diseases and potential therapeutic targets. Their use extends to drug screening, genetic studies, and the evaluation of potential gene therapies, making them essential for academic institutions and biotechnology companies alike.
Compared to alternative cell models, which may express the CCDC88B gene, the knockout versions uniquely provide a clear delineation of this gene's effects. This specificity minimizes background noise in experimental results and enhances data reliability, crucial for advancing research findings. Additionally, our cell lines come with robust documentation and validation data, ensuring researchers can confidently replicate our findings.
In conclusion, CCDC88B Gene Knockout Cell Lines represent a powerful addition to the toolbox of researchers and clinicians focused on gene function analysis and its implications in disease. Our company, with years of expertise in genetic engineering and cell line development, is committed to delivering high-quality products that propel scientific discovery forward.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.