Gene: CCDC65
Official Full Name: dynein regulatory complex subunit 2provided by HGNC
Gene Summary: This gene encodes a sperm tail protein that is highly expressed in adult testis, spermatocytes and spermatids. The protein plays a critical role in the assembly of the nexin-dynein regulatory complex. Mutations in this gene result in primary ciliary dyskinesia. [provided by RefSeq, Nov 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24174 | CCDC65 Knockout cell line (HCT 116) | Human | CCDC65 | 1:2~1:4 | Negative | Online Inquiry |
KO24175 | CCDC65 Knockout cell line (HEK293) | Human | CCDC65 | 1:3~1:6 | Negative | Online Inquiry |
KO24176 | CCDC65 Knockout cell line (A549) | Human | CCDC65 | 1:3~1:4 | Negative | Online Inquiry |
CCDC65 Gene Knockout Cell Lines represent a breakthrough tool in molecular biology, engineered to facilitate the study of the CCDC65 gene, which plays a critical role in cellular functions such as ciliary assembly and organization. These cell lines have been developed using state-of-the-art CRISPR-Cas9 technology, ensuring precise and efficient gene disruption. By targeting the CCDC65 gene, these knockout lines allow researchers to investigate the gene’s function and its implications in various biological processes, particularly those associated with ciliopathies and motile cilia disorders.
The primary mechanism of action behind the CCDC65 Gene Knockout Cell Lines is their ability to silence the expression of the CCDC65 gene, effectively mimicking loss-of-function phenotypes. This enables scientists to conduct functional assays to elucidate the gene's role in ciliary dynamics, cellular signaling pathways, and associated morphological changes. Such information is invaluable not just for fundamental biology but also for identifying potential therapeutic targets in diseases stemming from ciliary dysfunction.
In both research and clinical settings, these cell lines are instrumental for drug screening and pathway analysis, contributing to a better understanding of diseases that exhibit cilia-related defects. Unlike traditional models, which may not accurately reflect the complexity of human cellular behavior, CCDC65 Gene Knockout Cell Lines offer precise genetic control and consistent reproducibility, making them superior alternatives for experimental validation.
Researchers and clinicians can derive significant value from these cell lines, as they provide exceptional utility in elucidating genetic interactions and potential therapies for ciliopathies. The ability to explore complex cellular mechanisms in an efficient manner accelerates the pace of discovery and is particularly essential for advancing translational research.
Our company boasts extensive expertise in gene editing technology and cellular model systems, providing a robust portfolio of high-quality biological products designed to support innovative research. With a commitment to scientific excellence, we empower scientists and researchers to push the boundaries of their knowledge through tools that are tailored for precision and performance.
Please note that all services are for research use only. Not intended for any clinical use.
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