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CCDC181 Knockout Cell Lines

Gene: CCDC181

Official Full Name: coiled-coil domain containing 181provided by HGNC

Gene Summary: Predicted to enable microtubule binding activity. Predicted to be located in manchette and sperm flagellum. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18942 CCDC181 Knockout cell line (HEK293) Human CCDC181 1:3~1:6 Negative Online Inquiry

Background

CCDC181 Gene Knockout Cell Lines are specifically engineered cellular models that facilitate the investigation of the CCDC181 gene's biological roles and mechanisms. By employing advanced CRISPR/Cas9 gene-editing technology, these cell lines effectively disrupt the expression of CCDC181, allowing researchers to delineate its function within various physiological and pathological contexts.

The primary mechanism by which the CCDC181 knockout cell lines operate is through the precise deletion of exons within the CCDC181 gene. This genomic alteration results in the absence of functional protein, providing an invaluable tool to study gene function, signaling pathways, and cellular interactions. Researchers can utilize these models to observe phenotypic changes, signaling disruptions, or alterations in cellular behavior that occur when CCDC181 activity is compromised.

The scientific importance of CCDC181 Gene Knockout Cell Lines cannot be overstated; they have far-reaching applications in both fundamental research and clinical settings. In cancer research, for instance, understanding the role of CCDC181 can reveal insights into tumorigenesis, cell proliferation, and metastasis. Additionally, these cell lines can aid in drug discovery efforts by identifying potential therapeutic targets and elucidating drug mechanisms of action.

Compared to conventional methods of gene silencing such as RNA interference (RNAi) or the use of chemical inhibitors, the CCDC181 knockout cell lines offer a more robust and permanent solution. The knockout approach provides clearer insights into gene function, free from off-target effects commonly associated with transient knockdowns.

For researchers and clinicians focused on advancing the field of molecular biology and progressing towards novel therapeutic strategies, CCDC181 Gene Knockout Cell Lines present a superior model system that stimulates innovative research endeavors. Our company, with its expertise in genetic engineering and molecular biology, is dedicated to providing high-quality biological products that empower researchers to make significant scientific discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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