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CCDC180 Knockout Cell Lines

Gene: CCDC180

Official Full Name: coiled-coil domain containing 180provided by HGNC

Gene Summary: The protein encoded by this gene contains a coiled-coil domain. Alternative splicing results in multiple transcript variants encoding different isoforms. A single nucleotide polymorphism (SNP) in this gene has been associated with increased susceptibility to Behcet's Disease (PMID: 19442274). [provided by RefSeq, Dec 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18943 CCDC180 Knockout cell line (HeLa) Human CCDC180 1:3~1:6 Negative Online Inquiry
KO18944 CCDC180 Knockout cell line (HCT 116) Human CCDC180 1:2~1:4 Negative Online Inquiry

Background

CCDC180 Gene Knockout Cell Lines are genetically engineered cellular models that facilitate the study of CCDC180 gene function by completely inactivating this particular gene. This product provides researchers with invaluable tools to explore the implications of CCDC180 dysregulation in various biological processes and associated diseases, such as cancer and metabolic disorders. The knockout model allows precise observations of cellular behavior, revealing important pathways and interactions that the CCDC180 gene may influence.

The key function of these cell lines lies in their ability to mimic the physiological conditions of gene knockout in a controlled laboratory environment. Utilizing advanced CRISPR-Cas9 gene editing technology, the CCDC180 gene is effectively removed, enabling researchers to examine phenotypic changes, gene expression profiles, and signaling pathways devoid of CCDC180’s influence. By leveraging these models, scientists can gain insights into the gene's role in cell proliferation, differentiation, and apoptosis.

The scientific importance of CCDC180 Gene Knockout Cell Lines extends to both basic and applied research. In clinical settings, this product can assist in drug development and personalized medicine approaches, allowing for the identification of potential therapeutic targets. Moreover, understanding the biological functions of CCDC180 could reveal critical mechanisms underlying various pathologies, providing a pathway for innovative interventions.

What sets CCDC180 Gene Knockout Cell Lines apart from alternative products is their high specificity and reproducibility, paired with comprehensive supportive documentation. The rigorous validation process and detailed characterization ensure reliable and consistent results, significantly reducing the variability often observed in genetically modified models.

Researchers and clinicians will find immense value in these cell lines as they expedite the quest for significant findings that could translate into clinical applications. By offering a reliable platform conducive to rigorous scientific inquiry, CCDC180 Gene Knockout Cell Lines empower users to deepen their understanding of genetic influences on health and disease.

With a commitment to excellence and innovation, our company specializes in providing high-quality biological products, ensuring that researchers have the tools necessary to drive discovery and advance scientific knowledge.

Please note that all services are for research use only. Not intended for any clinical use.

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