Gene: CASTOR1
Official Full Name: cytosolic arginine sensor for mTORC1 subunit 1provided by HGNC
Gene Summary: Enables several functions, including arginine binding activity; identical protein binding activity; and protein sequestering activity. Involved in cellular response to L-arginine; cellular response to amino acid starvation; and regulation of TORC1 signaling. Located in GATOR2 complex and cytosol. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO09198 | CASTOR1 Knockout cell line (HeLa) | Human | CASTOR1 | 1:3~1:6 | Negative | Online Inquiry |
KO09199 | CASTOR1 Knockout cell line (HCT 116) | Human | CASTOR1 | 1:2~1:4 | Negative | Online Inquiry |
KO09200 | CASTOR1 Knockout cell line (HEK293) | Human | CASTOR1 | 1:3~1:6 | Negative | Online Inquiry |
KO09201 | CASTOR1 Knockout cell line (A549) | Human | CASTOR1 | 1:3~1:4 | Negative | Online Inquiry |
CASTOR1 Gene Knockout Cell Lines are genetically engineered cells designed to specifically ablate the CASTOR1 gene, which plays a crucial role in various cellular processes including immune responses and stress regulation. These cell lines are crafted using advanced CRISPR-Cas9 technology, allowing for precise edits in the genomic DNA, ensuring that the CASTOR1 locus is efficiently disrupted. This targeted gene knockout model provides researchers with a vital tool to explore the functional consequences of CASTOR1 deficiency, offering insights into its contributions to physiological and pathological processes.
The primary mechanism by which CASTOR1 Gene Knockout Cell Lines operate is through the deliberate interruption of gene expression. By silencing CASTOR1, these cells enable the investigation of downstream signaling pathways, protein interactions, and metabolic shifts that may arise from the absence of this gene. This functionality makes them invaluable in both research and clinical contexts, allowing for enhanced studies on immune modulation, cancer biology, and cellular stress responses.
In comparison to alternative gene editing models, CASTOR1 Gene Knockout Cell Lines offer several distinct advantages. They demonstrate higher efficiency in knockout generation, a more consistent phenotype across replicated experiments, and the ability to incorporate additional genetic modifications. Furthermore, these cell lines can be seamlessly integrated into various assays, including drug screening and functional studies, facilitating a comprehensive understanding of the underlying biology related to CASTOR1.
For researchers and clinicians seeking to elucidate the role of CASTOR1 in health and disease, these knockout cell lines represent a strategic investment. Their availability supports a wide spectrum of applications, from basic biological research to translational studies that may influence therapeutic strategies.
Our company prides itself on delivering high-quality biological products, backed by rigorous validation and a commitment to advancing scientific knowledge. We specialize in creating unique genetic models that empower researchers to enhance their studies, making breakthroughs in understanding complex biological systems possible.
Please note that all services are for research use only. Not intended for any clinical use.
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