Gene: CASP8AP2
Official Full Name: caspase 8 associated protein 2provided by HGNC
Gene Summary: This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Nov 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19066 | CASP8AP2 Knockout cell line (HeLa) | Human | CASP8AP2 | 1:3~1:6 | Negative | Online Inquiry |
KO19067 | CASP8AP2 Knockout cell line (HCT 116) | Human | CASP8AP2 | 1:2~1:4 | Negative | Online Inquiry |
KO19068 | CASP8AP2 Knockout cell line (HEK293) | Human | CASP8AP2 | 1:3~1:6 | Negative | Online Inquiry |
KO19069 | CASP8AP2 Knockout cell line (A549) | Human | CASP8AP2 | 1:3~1:4 | Negative | Online Inquiry |
CASP8AP2 Gene Knockout Cell Lines are innovative biological tools designed to facilitate in-depth research into the role of the CASP8AP2 gene in cellular processes and disease mechanisms. These cell lines have been engineered to ablate the expression of the CASP8AP2 gene, a critical component involved in apoptosis and immune response regulation. By creating a knockout model, researchers can investigate the functional consequences of CASP8AP2 deficiency, providing insights into pathways associated with cancer, neurodegenerative diseases, and immune disorders.
The primary mechanism involves the targeted mutation of the CASP8AP2 gene, effectively disabling its function. Researchers can employ these cell lines to assess alterations in cell survival, proliferation, and apoptotic responses, ultimately generating valuable data on gene function and cellular behavior under various experimental conditions. Through such models, the accountability of CASP8AP2 in various signaling pathways can be elucidated, laying groundwork for potential therapeutic interventions.
The scientific importance of CASP8AP2 Gene Knockout Cell Lines extends to both research and clinical realms. In research settings, they serve as indispensable tools for functional genomics and pharmacological studies, allowing scientists to unravel the complexities of gene interactions and drug responses. In clinical settings, understanding the role of CASP8AP2 may lead to novel biomarkers for diagnosis or targets for therapeutic strategies.
One of the significant advantages of our CASP8AP2 Gene Knockout Cell Lines is the precision with which gene editing has been achieved, resulting in a model that closely mirrors physiological conditions. Unlike traditional methods, our cell lines offer a stable and reproducible tool for long-term studies. Additionally, our robust validation process ensures consistent quality and performance, setting our product apart from competitors.
For researchers, clinicians, and biotech companies aiming to drive discovery in the fields of cancer research and beyond, these knockout cell lines represent a strategic asset in unraveling the intricacies of gene function. By providing a reliable model, we empower scientific exploration and innovation. Our company's dedication to excellence in biological research tools underscores our commitment to advancing the scientific community's efforts in disease understanding and therapeutic development.
Please note that all services are for research use only. Not intended for any clinical use.
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