Gene: CARD6
Official Full Name: caspase recruitment domain family member 6provided by HGNC
Gene Summary: This gene encodes a protein that contains a caspase recruitment domain (CARD), an antiparallel six-helical bundle that mediates homotypic protein-protein interactions. The encoded protein is a microtubule-associated protein that has been shown to interact with receptor-interacting protein kinases and positively modulate signal transduction pathways converging on activation of the inducible transcription factor NF-kB. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24736 | CARD6 Knockout cell line (HeLa) | Human | CARD6 | 1:3~1:6 | Negative | Online Inquiry |
KO24737 | CARD6 Knockout cell line (HEK293) | Human | CARD6 | 1:3~1:6 | Negative | Online Inquiry |
KO24738 | CARD6 Knockout cell line (A549) | Human | CARD6 | 1:3~1:4 | Negative | Online Inquiry |
CARD6 Gene Knockout Cell Lines are meticulously engineered cellular models designed to facilitate the study of the CARD6 gene, a critical component in various biological processes, including immune regulation and inflammation. These cell lines are generated using advanced CRISPR/Cas9 technology, enabling the targeted disruption of the CARD6 gene to investigate its functional roles in cellular pathways. By effectively eliminating CARD6 expression, researchers can explore downstream effects on signaling cascades, apoptosis, and responses to pathogenic stimuli.
The primary function of these knockout cell lines is to provide a robust platform for elucidating the mechanisms by which CARD6 influences immune responses, particularly in the context of diseases such as cancer and autoimmune disorders. As CARD6 interacts with multiple proteins within the NF-κB signaling pathway, its knockout allows for a clearer understanding of the genetic interactions and the resultant phenotypic changes in cellular behavior. This specificity is crucial for both basic research and translational applications, enabling targeted therapy developments and biomarker identification.
The scientific importance of CARD6 Gene Knockout Cell Lines lies in their ability to bridge the gap between experimental hypothesis and clinical applications. Their use can accelerate drug discovery processes by helping to identify novel therapeutic targets and by facilitating the validation of potential treatments in a controlled environment.
Compared to conventional methods, such as RNA interference or pharmacological inhibitors, CARD6 knockout lines offer complete gene deletion, allowing for more conclusive analyses of gene function and downstream effects. They provide high reproducibility and well-defined genetic backgrounds, reducing variability that often complicates results in other models.
For researchers and clinicians, the value of CARD6 Gene Knockout Cell Lines is undeniable. They empower the scientific community to unravel complex biological questions and contribute to the development of cutting-edge therapeutic strategies. The opportunity to study gene function in a highly controlled manner not only advances fundamental understanding but also fosters innovation in precision medicine.
Our company prides itself on its commitment to delivering high-quality biological products backed by rigorous scientific validation. With expertise in genetic engineering and cellular biology, we provide cutting-edge tools like the CARD6 Gene Knockout Cell Lines to support research at the forefront of biomedical science.
Please note that all services are for research use only. Not intended for any clinical use.
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