Gene: CAPZA1
Official Full Name: capping actin protein of muscle Z-line subunit alpha 1provided by HGNC
Gene Summary: CAPZA1 is a member of the F-actin capping protein alpha subunit family. This gene encodes the alpha subunit of the barbed-end actin binding protein. The protein regulates growth of the actin filament by capping the barbed end of growing actin filaments. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO04824 | CAPZA1 Knockout cell line (HeLa) | Human | CAPZA1 | 1:3~1:6 | Negative | Online Inquiry |
KO04825 | CAPZA1 Knockout cell line (HCT 116) | Human | CAPZA1 | 1:2~1:4 | Negative | Online Inquiry |
KO04826 | CAPZA1 Knockout cell line (HEK293) | Human | CAPZA1 | 1:3~1:6 | Negative | Online Inquiry |
KO04827 | CAPZA1 Knockout cell line (A549) | Human | CAPZA1 | 1:3~1:4 | Negative | Online Inquiry |
CAPZA1 Gene Knockout Cell Lines are specialized cellular models engineered to lack the CAPZA1 gene, which encodes the cap-binding protein CAPZ. This product plays a critical role in the actin cytoskeleton dynamics, influencing processes such as cell motility, proliferation, and signal transduction. The knockout of CAPZA1 leads to alterations in cellular architecture and function, allowing researchers to investigate the specific contributions of this protein in various biological contexts.
These cell lines operate through mechanisms that disrupt normal filamentous actin regulation, fundamentally impacting cellular behaviors. Researchers leveraging CAPZA1 Gene Knockout Cell Lines can explore how disruptions in actin dynamics affect critical processes such as tumor progression, migration, and immune responses. The significance of these investigations extends to understanding diseases like cancer, where aberrant cell motility and structure are pivotal.
The scientific importance of this product is underscored by its potential applications in basic research, drug development, and therapeutic interventions. Without CAPZA1, researchers can model diseases associated with cytoskeletal defects, offering new insights into molecular pathways that contribute to pathologies. Compared to existing models, the CAPZA1 knockout lines provide a unique and precise approach to dissect the role of actin-binding proteins.
This product stands out due to its ability to provide a specific genetic context for experiments, significantly improving the translational relevance of findings in a controlled environment. Researchers and clinicians benefit from this specific gene knockout as it offers clarity in elucidating CAPZA1's role, which is often obscured in less defined models.
Our company specializes in the development of advanced biological products and solutions, with a focus on supporting innovative research and clinical applications that drive scientific discovery. Through our state-of-the-art gene editing technologies, we are committed to delivering high-quality, reliable cell models that enhance research capabilities and contribute to the advancement of the biological sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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