Gene: CAPRIN1
Official Full Name: cell cycle associated protein 1provided by HGNC
Gene Summary: Enables several functions, including ATP binding activity; molecular condensate scaffold activity; and signaling adaptor activity. Involved in membraneless organelle assembly; positive regulation of stress granule assembly; and regulation of gene expression. Located in cell leading edge and cytosol. Is active in intracellular membraneless organelle. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO00989 | CAPRIN1 Knockout cell line (A549) | Human | CAPRIN1 | 1:3~1:4 | Negative | Online Inquiry |
KO36748 | CAPRIN1 Knockout cell line (HeLa) | Human | CAPRIN1 | 1:3~1:6 | Negative | Online Inquiry |
KO36749 | CAPRIN1 Knockout cell line (HCT 116) | Human | CAPRIN1 | 1:2~1:4 | Negative | Online Inquiry |
KO36750 | CAPRIN1 Knockout cell line (HEK293) | Human | CAPRIN1 | 1:3~1:6 | Negative | Online Inquiry |
CAPRIN1 Gene Knockout Cell Lines are specifically engineered cellular models that lack the expression of the CAPRIN1 gene, which encodes for a critical RNA-binding protein involved in various cellular processes. These knockout cell lines serve as invaluable tools for the study of gene function, cellular signaling pathways, and the roles of CAPRIN1 in physiological and pathological contexts. By creating a context where CAPRIN1 is ablated, researchers can dissect the downstream effects and elucidate its contributions to cellular homeostasis, stress responses, and potential involvement in diseases such as cancer.
The mechanism of action for these knockout cell lines revolves around the complete absence of CAPRIN1 protein, allowing researchers to observe the subsequent effects on gene expression, cell proliferation, and stress granule dynamics. The loss of CAPRIN1 affects mRNA localization and translation regulation, which can lead to significant insights into post-transcriptional control mechanisms. Available for various species, including human and mouse-derived cell lines, these products make it easier for investigators to implement experiments that require consistent and reliable cell culture systems.
Scientifically, CAPRIN1 Gene Knockout Cell Lines are invaluable for both basic and applied research. They can be utilized to explore therapeutic targets, validate drug candidates, or investigate the molecular underpinnings of CAPRIN1-associated diseases. The ability to phenotype these cells offers a substantial advantage in both academic and clinical settings, where understanding gene function and interactions is paramount.
Compared to alternative cell lines that retain CAPRIN1 expression, our knockout models provide a higher degree of experimental specificity. By using CAPRIN1-deficient cells, researchers can obtain more relevant data without the confounding effects of the protein's presence. This specificity enhances the reproducibility of results, contributing to the reliability of research findings.
For researchers and clinicians seeking comprehensive insights into RNA-binding protein functionality and its implications in human health, CAPRIN1 Gene Knockout Cell Lines stand as a premier option. Our expertise in developing innovative biological tools ensures that you are equipped with the highest quality products tailored to your experimental needs. Our commitment to producing reliable and informative biological models underlines our dedication to advancing scientific research and exploration.
Please note that all services are for research use only. Not intended for any clinical use.
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