Gene: CALM3
Official Full Name: calmodulin 3provided by HGNC
Gene Summary: This gene encodes a member of a family of proteins that binds calcium and functions as a enzymatic co-factor. Activity of this protein is important in the regulation of the cell cycle and cytokinesis. Multiple alternatively spliced transcript variants have been observed at this gene. [provided by RefSeq, Aug 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO09001 | CALM3 Knockout cell line (HeLa) | Human | CALM3 | 1:3~1:6 | Negative | Online Inquiry |
KO09002 | CALM3 Knockout cell line (HCT 116) | Human | CALM3 | 1:2~1:4 | Negative | Online Inquiry |
KO09003 | CALM3 Knockout cell line (HEK293) | Human | CALM3 | 1:3~1:6 | Negative | Online Inquiry |
KO09004 | CALM3 Knockout cell line (A549) | Human | CALM3 | 1:3~1:4 | Negative | Online Inquiry |
CALM3 Gene Knockout Cell Lines are specialized cellular models engineered to target and disrupt the CALM3 gene, which encodes a protein critical for calcium signaling and various cellular processes. These knockout cell lines have been created using advanced CRISPR-Cas9 gene editing technology, providing researchers with a reliable tool to investigate the functional implications of CALM3 loss on cellular behavior, signal transduction, and disease mechanisms.
The functionality of CALM3 Gene Knockout Cell Lines allows for a clearer understanding of the underlying pathways in calcium homeostasis and their roles in physiological and pathological states. By effectively silencing the CALM3 gene, researchers can study how its absence impacts cell proliferation, apoptosis, and stress response mechanisms. This is particularly relevant in cancer research, neurobiology, and developmental biology, where aberrant calcium signaling can lead to significant disease outcomes.
Scientifically, CALM3 knockout models are pivotal in identifying therapeutic targets and evaluating novel drug responses. They provide an indispensable resource for elucidating the role of CALM3 in cellular processes such as synaptic transmission and cardiovascular function. Moreover, these knockout lines can facilitate the development of experimental strategies tailored towards therapies for diseases associated with calcium dysregulation.
In comparison to traditional methods that involve gene silencing via RNA interference, CALM3 Gene Knockout Cell Lines provide a more stable and permanent gene alteration, enhancing reproducibility and reducing variability in experimental outcomes. Their use can lead to more definitive conclusions regarding gene function and its implications in disease, offering researchers a more powerful approach to study genetic contributions in health and illness.
The value of CALM3 Gene Knockout Cell Lines is underscored by their potential to drive innovative research and therapeutic advancements. By choosing our product, researchers and clinicians gain access to high-quality, rigorously validated models from a company with extensive expertise in genetic engineering and biological research. Our commitment to supporting scientific inquiry ensures that our products meet the complex demands of today’s research landscape, enabling progress in understanding and treating diseases at their genetic roots.
Please note that all services are for research use only. Not intended for any clinical use.
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