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C1orf35 Knockout Cell Lines

Gene: C1orf35

Official Full Name: chromosome 1 open reading frame 35provided by HGNC

Gene Summary: Enables RNA binding activity. Predicted to be located in extracellular region; ficolin-1-rich granule lumen; and secretory granule lumen. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO19339 C1orf35 Knockout cell line (HeLa) Human C1orf35 1:3~1:6 Negative Online Inquiry
KO19340 C1orf35 Knockout cell line (HCT 116) Human C1orf35 1:2~1:4 Negative Online Inquiry
KO19341 C1orf35 Knockout cell line (HEK293) Human C1orf35 1:3~1:6 Negative Online Inquiry
KO19342 C1orf35 Knockout cell line (A549) Human C1orf35 1:3~1:4 Negative Online Inquiry

Background

C1orf35 Gene Knockout Cell Lines are meticulously engineered cellular models that enable researchers to study the functional consequences of the loss of the C1orf35 gene. This product harnesses the power of CRISPR-Cas9 genome editing technology to generate a precise knockout of the C1orf35 gene across various cell types. By selectively removing this gene, the cell lines provide vital insights into its role in cellular processes such as differentiation, proliferation, and response to stressors.

The primary mechanism of action involves the introduction of guide RNA (gRNA) specific to the C1orf35 gene, facilitating the Cas9 endonuclease to create double-strand breaks at the target site. This process leads to non-homologous end joining (NHEJ) repair pathways, effectively disrupting the coding sequence of the gene, thus producing a null phenotype. As a result, these knockout cell lines serve as powerful tools for elucidating gene function and pathophysiological mechanisms associated with C1orf35.

The scientific importance of C1orf35 Gene Knockout Cell Lines extends to diverse research arenas, including cancer biology, neurobiology, and cell signaling pathways. By employing these cell lines, researchers can explore the implications of C1orf35 in disease models and potential therapeutic interventions, making them invaluable in both academic and pharmaceutical research settings.

Compared to traditional knockout models, C1orf35 Gene Knockout Cell Lines offer a streamlined and scalable approach, significantly reducing the time and resources typically needed for generating and validating gene knockouts. Moreover, our cell lines are extensively characterized to ensure consistent performance, providing researchers with confidence in their experimental outcomes.

The value of C1orf35 Gene Knockout Cell Lines is further evident in their capacity to enhance understanding of genetic interactions and disease mechanisms, thereby supporting the development of targeted treatments. By utilizing these advanced cell lines, researchers and clinicians can accelerate their discoveries and translate findings into real-world applications more efficiently.

As a leader in the field of genetic engineering, our company specializes in providing high-quality biological products that empower researchers to push the boundaries of science. Our commitment to scientific excellence ensures that customers receive not only top-tier products but also the support required to maximize their research potential.

Please note that all services are for research use only. Not intended for any clinical use.

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