Gene: C19orf12
Official Full Name: chromosome 19 open reading frame 12provided by HGNC
Gene Summary: This gene encodes a small transmembrane protein. Mutations in this gene are a cause of neurodegeneration with brain iron accumulation-4 (NBIA4), but the specific function of the encoded protein is unknown. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25420 | C19orf12 Knockout cell line (HeLa) | Human | C19orf12 | 1:3~1:6 | Negative | Online Inquiry |
KO25421 | C19orf12 Knockout cell line (HCT 116) | Human | C19orf12 | 1:2~1:4 | Negative | Online Inquiry |
KO25422 | C19orf12 Knockout cell line (HEK293) | Human | C19orf12 | 1:3~1:6 | Negative | Online Inquiry |
KO25423 | C19orf12 Knockout cell line (A549) | Human | C19orf12 | 1:3~1:4 | Negative | Online Inquiry |
C19orf12 Gene Knockout Cell Lines are specialized cellular models in which the C19orf12 gene has been inactivated using targeted gene-editing technologies such as CRISPR/Cas9. This gene is implicated in various metabolic and neurodegenerative disorders, and the creation of knockout cell lines serves as a powerful tool for studying the biological roles of this gene in cellular pathways and disease mechanisms.
The primary function of these cell lines lies in their ability to facilitate comprehensive investigations into gene function and its implications in pathology. By studying these knockout cell lines, researchers can elucidate the molecular mechanisms of diseases related to C19orf12, particularly within the realms of neurobiology and metabolism. This enables scientists to investigate how the absence of this gene affects various cellular processes, such as mitochondrial function, lipid metabolism, and cellular stress responses.
From a scientific perspective, the significance of C19orf12 Gene Knockout Cell Lines is profound, as they allow for the development of new therapeutic strategies and enhance our understanding of the etiology of diseases. In clinical research, they can be utilized for drug screening and for understanding drug interactions within a controlled environment, leading to more effective treatment protocols.
What sets C19orf12 knockout cell lines apart from alternative models is their specificity and precision. This product provides a clean genetic background, reducing the variability often present in natural mutations found in commonly used cell lines. Their design allows for reproducible results and increased reliability in experiments focused on gene function.
For researchers and clinicians, the value of utilizing C19orf12 Gene Knockout Cell Lines is underscored by the ability to generate high-quality data that can advance both basic and translational research. The potential to unlock new insights into critical cellular processes places this product at the forefront of biomedical research.
Our company specializes in providing high-quality, genetically engineered cell lines, backed by extensive expertise in molecular biology and gene editing technologies. We are committed to delivering state-of-the-art products that empower researchers to achieve breakthrough discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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