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C17orf58 Knockout Cell Lines

Gene: C17orf58

Official Full Name: chromosome 17 open reading frame 58provided by HGNC

Gene Summary: Located in collagen-containing extracellular matrix. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO19167 C17orf58 Knockout cell line (HeLa) Human C17orf58 1:3~1:6 Negative Online Inquiry
KO19168 C17orf58 Knockout cell line (HCT 116) Human C17orf58 1:2~1:4 Negative Online Inquiry
KO19169 C17orf58 Knockout cell line (HEK293) Human C17orf58 1:3~1:6 Negative Online Inquiry

Background

C17orf58 Gene Knockout Cell Lines are specialized cell lines in which the C17orf58 gene has been functionally disrupted, enabling researchers to study the gene's biological role and its implications in various cellular processes. This gene is known to be involved in cellular signaling and metabolic pathways, making its knockout critical for understanding its contribution to normal cell function and disease states.

The key mechanism of these cell lines involves the removal or inactivation of the C17orf58 gene through advanced gene-editing techniques, such as CRISPR/Cas9. Researchers utilize these knockout models to investigate the downstream effects of C17orf58 loss on cellular behavior, gene expression profiles, and interactions with other signaling pathways. This allows for a comprehensive analysis of how alterations in this gene can lead to specific phenotypic changes, aiding in the exploration of its potential roles in cancer biology, neurodegenerative conditions, and other diseases.

In research and clinical settings, these cell lines are invaluable for drug discovery and development applications. By creating a controlled environment where C17orf58 is absent, scientists can assess the impact of therapeutic agents on cellular outcomes, ultimately contributing to the identification of novel targets for clinical intervention. Compared to traditional cell lines, which may exhibit complete or partial expression of the gene, the C17orf58 Gene Knockout Cell Lines provide a clear and unequivocal model for studying the loss of function.

The primary advantage of these knockout cell lines includes their specificity and control, reducing the possibility of off-target effects compared to other gene-editing strategies. Their utility in dissecting the complex biology involving C17orf58 makes them a valuable tool for both academic and pharmaceutical research, facilitating advancements toward personalized medicine and targeted therapies.

Utilizing our expertise in genetic engineering and commitment to providing high-quality research tools, we offer meticulously characterized C17orf58 Gene Knockout Cell Lines that empower scientists to unravel the complexities of gene function and advance research in cutting-edge areas of biology.

Please note that all services are for research use only. Not intended for any clinical use.

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