Gene: C14orf28
Official Full Name: dopamine receptor interacting protein 1provided by HGNC
Gene Summary: Predicted to act upstream of or within with a positive effect on NMDA selective glutamate receptor signaling pathway and cAMP-mediated signaling. Predicted to act upstream of or within several processes, including G protein-coupled dopamine receptor signaling pathway; memory; and neurogenesis. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28917 | C14orf28 Knockout cell line (HCT 116) | Human | C14orf28 | 1:2~1:4 | Negative | Online Inquiry |
KO28918 | C14orf28 Knockout cell line (A549) | Human | C14orf28 | 1:3~1:4 | Negative | Online Inquiry |
C14orf28 Gene Knockout Cell Lines are genetically engineered cellular models that facilitate the study of gene function by using targeted gene disruption techniques. By specifically knocking out the C14orf28 gene, these cell lines enable researchers to observe the resultant phenotypic changes, mutations, and alternative pathway activations, thereby providing critical insights into the gene’s biological roles and its implications in various cellular processes.
The key function of C14orf28 Gene Knockout Cell Lines lies in their ability to create a loss-of-function model for research purposes. The knockout is achieved via techniques such as CRISPR/Cas9 or homologous recombination, which precisely disrupt the coding sequence of the C14orf28 gene. This mechanism allows for a thorough investigation into how the absence of this gene alters cellular behavior, signaling pathways, and interaction with other genes, making it an invaluable tool for unraveling complex genetic networks.
In terms of scientific importance, these cell lines play a crucial role in cancer research, developmental biology, and gene therapy studies. They enable researchers to elucidate the C14orf28 gene’s role in disease mechanisms, investigate potential therapeutic targets, and assess novel treatment strategies in preclinical settings. Furthermore, they can be utilized to evaluate modifications in metabolic processes that may contribute to pathologies linked with gene aberrations.
Compared to traditional cell models, C14orf28 Gene Knockout Cell Lines offer specific advantages, such as reduced variability due to standardized genetic modifications and enhanced reproducibility of experimental outcomes. In contrast to other gene editing techniques that may result in off-target effects, these cell lines provide a more reliable platform for in-depth functional studies.
For researchers and clinicians, the value of C14orf28 Gene Knockout Cell Lines cannot be overstated. They streamline investigations and enhance the ability to make data-driven decisions in therapeutic development. Their robustness makes them ideal for high-throughput screening and mechanistic studies, providing a substantial return on investment in terms of fundamental and applied biological research.
Our company specializes in providing high-quality, custom-engineered cell lines tailored for specific research needs, backed by a strong foundation in molecular genetics. By leveraging our expertise, researchers can confidently explore the complexities of gene functionality and its implications in health and disease.
Please note that all services are for research use only. Not intended for any clinical use.
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