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BMERB1 Knockout Cell Lines

Gene: BMERB1

Official Full Name: bMERB domain containing 1provided by HGNC

Gene Summary: Predicted to be involved in negative regulation of microtubule depolymerization. Predicted to act upstream of or within negative regulation of cell motility involved in cerebral cortex radial glia guided migration. Predicted to be active in microtubule cytoskeleton. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23894 BMERB1 Knockout cell line (HeLa) Human BMERB1 1:3~1:6 Negative Online Inquiry
KO23895 BMERB1 Knockout cell line (HCT 116) Human BMERB1 1:2~1:4 Negative Online Inquiry
KO23896 BMERB1 Knockout cell line (HEK293) Human BMERB1 1:3~1:6 Negative Online Inquiry
KO23897 BMERB1 Knockout cell line (A549) Human BMERB1 1:3~1:4 Negative Online Inquiry

Background

BMERB1 Gene Knockout Cell Lines represent a state-of-the-art tool for investigating the biological functions and pathways associated with the BMERB1 gene. These cell lines have been specifically engineered to lack the BMERB1 gene, allowing researchers to elucidate its role in cellular processes, signaling pathways, and disease mechanisms. By effectively creating a loss-of-function model, BMERB1 knockout cell lines serve to clarify the gene's contribution to various biological phenomena, facilitating a deeper understanding of gene function and interaction.

The primary mechanism of these knockout cell lines involves the targeted deletion of the BMERB1 gene using advanced genetic engineering techniques such as CRISPR-Cas9 or homologous recombination, both of which create precise and reproducible genetic alterations. Researchers can deploy these cell lines in a multitude of assays, including proliferation, apoptosis, and cellular response to various stimuli, thereby offering insights into the gene's influence on cell viability, differentiation, and pathology.

These cell lines hold significant scientific importance, particularly in research contexts exploring cancer biology, metabolic disorders, and genetic syndromes. The ability to manipulate and study gene function in a controlled environment allows scientists to make substantial progress in drug discovery, gene therapy, and personalized medicine approaches.

Compared to alternative models, such as transient knockdowns or overexpression systems, BMERB1 Gene Knockout Cell Lines provide more stable and enduring genetic modifications, thus yielding more consistent and reliable data over extended experimental periods. This longevity enhances experimental reproducibility, a critical factor in scientific research.

The value of BMERB1 Gene Knockout Cell Lines is further underscored by their versatility and accessibility. Researchers and clinicians alike can leverage these lines to develop novel therapeutic strategies, understand disease mechanisms better, and validate potential drug targets.

Our company is a leader in providing high-quality biological tools, committed to advancing research through innovative solutions. With our expertise in genetic engineering and cell line development, we ensure that our BMERB1 Gene Knockout Cell Lines are rigorously validated and optimized to meet the needs of the scientific community, facilitating groundbreaking discoveries in molecular biology and translational research.

Please note that all services are for research use only. Not intended for any clinical use.

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