Gene: BICD2
Official Full Name: BICD cargo adaptor 2provided by HGNC
Gene Summary: This gene is one of two human homologs of Drosophila bicaudal-D and a member of the Bicoid family. It has been implicated in dynein-mediated, minus end-directed motility along microtubules. It has also been reported to be a phosphorylation target of NIMA related kinase 8. Two alternative splice variants have been described. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29496 | BICD2 Knockout cell line (HeLa) | Human | BICD2 | 1:3~1:6 | Negative | Online Inquiry |
KO29497 | BICD2 Knockout cell line (HCT 116) | Human | BICD2 | 1:2~1:4 | Negative | Online Inquiry |
KO29498 | BICD2 Knockout cell line (HEK293) | Human | BICD2 | 1:3~1:6 | Negative | Online Inquiry |
KO29499 | BICD2 Knockout cell line (A549) | Human | BICD2 | 1:3~1:4 | Negative | Online Inquiry |
BICD2 Gene Knockout Cell Lines are specialized cellular models that have been genetically engineered to specifically disrupt the BICD2 gene, which plays a crucial role in intracellular transport processes, particularly in the transport of organelles and essential proteins within the cell. These cell lines provide researchers with a robust platform to investigate the downstream effects of BICD2 deficiency, including the subsequent impacts on cellular signaling, organelle distribution, and overall cellular morphology.
The primary function of BICD2 is to facilitate the dynein-mediated transport of cargo along microtubules, a vital mechanism for maintaining cellular homeostasis and proper distribution of cellular components. By employing these knockout cell lines, scientists can elucidate the role of BICD2 in various biological processes such as cell division, neuronal function, and development, providing insights that are essential for understanding complex diseases, particularly neurodegenerative disorders where intracellular transport is compromised.
In research and clinical settings, BICD2 Gene Knockout Cell Lines are invaluable for studying gene function, validating potential drug targets, and screening for therapeutic compounds. Their application spans various fields, including neuroscience, cancer research, and developmental biology, making them a versatile tool in the life sciences.
Compared to alternative models such as wild-type cells or those with partial gene silencing, BICD2 knockout lines offer a more definitive approach to studying gene function without the confounding effects of residual gene activity. This heightened specificity enhances the reliability of experimental outcomes, making these cell lines an essential asset for researchers seeking high-quality, reproducible results.
The unique selling point of BICD2 Gene Knockout Cell Lines lies in their capacity to dissect the pathophysiological roles of BICD2 in a controlled environment, enabling researchers to advance their understanding of genetic influences on cellular pathways. In turn, this can lead to the development of novel therapeutic interventions.
Our company is committed to advancing scientific research by providing top-tier biological products. With extensive expertise in genetic engineering and cell line development, we deliver high-quality tools that empower researchers and clinicians in their endeavors to push the boundaries of biomedical knowledge.
Please note that all services are for research use only. Not intended for any clinical use.
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