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BEAN1 Knockout Cell Lines

Gene: BEAN1

Official Full Name: brain expressed associated with NEDD4 1provided by HGNC

Gene Summary: The protein encoded by this gene is one of several proteins that interact with NEDD4, a member of a family of ubiquitin-protein ligases. These proteins have PY motifs in common that bind to the WW domains of NEDD4. NEDD4 is developmentally regulated, and is highly expressed in embryonic tissues. Mutations in this gene (i.e., intronic insertions of >100 copies of pentanucleotide repeats including a (TGGAA)n sequence) are associated with spinocerebellar ataxia type 31. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24008 BEAN1 Knockout cell line (A549) Human BEAN1 1:3~1:4 Negative Online Inquiry

Background

BEAN1 Gene Knockout Cell Lines are precisely engineered cellular models that enable researchers to investigate the functional role of the BEAN1 gene within various biological contexts. Utilizing advanced CRISPR-Cas9 gene-editing technology, these cell lines have been developed to facilitate the study of BEAN1's involvement in cellular processes, such as immune responses and apoptosis, by eliminating the gene's expression and observing resultant phenotypic changes.

The key mechanisms at play in these knockout cell lines involve targeted disruption of the BEAN1 gene, leading to a complete loss of its protein product. This allows for a detailed examination of pathways and interactions in which BEAN1 participates, shedding light on its contribution to diseases such as neurodegeneration and cancer. Using these cell lines, researchers can perform functional assays, gene expression analyses, and drug response testing, creating an invaluable resource for both basic research and translational applications.

The scientific importance of BEAN1 Gene Knockout Cell Lines cannot be underestimated. They provide vital insights that can guide the development of novel therapeutic strategies and the identification of new biomarkers for various diseases. Their application in clinical research is poised to enhance our understanding of disease mechanisms and pave the path for precision medicine.

Compared to conventional approaches, our BEAN1 Gene Knockout Cell Lines offer unparalleled specificity and reproducibility in results. Unlike transient knockdown methods, these stable cell lines ensure persistent gene loss, thereby providing a more reliable platform for long-term studies. Furthermore, they are meticulously characterized, ensuring consistent performance across experiments.

For researchers and clinicians looking to delve into the intricate mechanisms of gene function and associated pathways, BEAN1 Gene Knockout Cell Lines present a critical tool. They are designed to streamline workflows, enhance data quality, and ultimately drive innovation in biological research. Our company stands at the forefront of gene-editing technology and is committed to delivering high-quality biological products that support scientific advancement.

Please note that all services are for research use only. Not intended for any clinical use.

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