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BDH2 Knockout Cell Lines

Gene: BDH2

Official Full Name: 3-hydroxybutyrate dehydrogenase 2provided by HGNC

Gene Summary: Enables 3-hydroxybutyrate dehydrogenase activity and NAD binding activity. Involved in epithelial cell differentiation and fatty acid beta-oxidation. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO19459 BDH2 Knockout cell line (HeLa) Human BDH2 1:3~1:6 Negative Online Inquiry
KO19460 BDH2 Knockout cell line (HCT 116) Human BDH2 1:2~1:4 Negative Online Inquiry
KO19461 BDH2 Knockout cell line (HEK293) Human BDH2 1:3~1:6 Negative Online Inquiry
KO19462 BDH2 Knockout cell line (A549) Human BDH2 1:3~1:4 Negative Online Inquiry

Background

BDH2 Gene Knockout Cell Lines represent a revolutionary tool for researchers looking to elucidate the biological functions of the BDH2 gene, which plays a critical role in cellular metabolism and energy regulation. These genetically modified cell lines are created using advanced CRISPR/Cas9 technology to precisely delete the BDH2 gene, allowing for an in-depth study of its contributions to metabolic pathways and potential implications in various diseases, including cancer and metabolic disorders.

The BDH2 gene encodes for a mitochondrial enzyme involved in the β-hydroxybutyrate dehydrogenase pathway, which is vital for cellular respiration and energy production. Knocking out this gene disrupts normal metabolic processes, thereby providing researchers with a unique opportunity to observe the phenotypic and molecular changes that arise in its absence. This functional elucidation is pivotal not only for understanding fundamental cellular mechanisms but also for exploring potential therapeutic targets.

In both research and clinical settings, BDH2 Gene Knockout Cell Lines facilitate innovative experiments, including drug screening assays and metabolic profiling, paving the way for novel treatments and diagnostics. Unlike traditional gene silencing methods, the knockout approach ensures heritable and stable changes, leading to reproducible results crucial for long-term studies.

These cell lines offer several advantages over existing alternatives, including enhanced specificity in genetic manipulation, improved reliability of experimental outcomes, and the capacity for scalable applications. The precise gene editing technology used ensures minimal off-target effects, raising the standard of accuracy in experimental design.

For researchers and clinicians striving to unravel complex biological questions or develop new therapeutic strategies, BDH2 Gene Knockout Cell Lines are invaluable resources that enable meticulous investigation. With our strong expertise in genetic engineering and commitment to quality, we stand ready to support your research endeavors by providing leading-edge biological products tailored to advance discovery and innovation in life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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