Gene: BCLAF3
Official Full Name: BCLAF1 and THRAP3 family member 3provided by HGNC
Gene Summary: Predicted to enable DNA binding activity and transcription coregulator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in mitochondrion. Predicted to be part of mediator complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21033 | BCLAF3 Knockout cell line (HeLa) | Human | BCLAF3 | 1:3~1:6 | Negative | Online Inquiry |
KO21034 | BCLAF3 Knockout cell line (HCT 116) | Human | BCLAF3 | 1:2~1:4 | Negative | Online Inquiry |
KO21035 | BCLAF3 Knockout cell line (HEK293) | Human | BCLAF3 | 1:3~1:6 | Negative | Online Inquiry |
KO21036 | BCLAF3 Knockout cell line (A549) | Human | BCLAF3 | 1:3~1:4 | Negative | Online Inquiry |
BCLAF3 Gene Knockout Cell Lines are specifically engineered cellular models designed to facilitate the study of the BCLAF3 gene, which is key to understanding its roles in apoptosis, cellular stress responses, and gene regulation. These cell lines leverage CRISPR-Cas9 technology to create precise gene knockouts, allowing researchers to investigate the functional consequences of BCLAF3 loss in various biological contexts.
The primary function of these knockout cell lines is to elucidate the pathways influenced by BCLAF3, a protein implicated in transcriptional regulation and stress response mechanisms. By removing the expression of the BCLAF3 gene, researchers can observe alterations in cell behavior, gene expression profiles, and cellular responses to stressors, providing valuable insights into mechanisms of disease, particularly in cancer and neurodegenerative disorders.
The scientific significance of BCLAF3 Gene Knockout Cell Lines is underscored by their potential applications in both basic research and clinical settings. These models can be used to screen for novel therapeutic targets, assess drug responses, and improve our understanding of pathological mechanisms in diseases where BCLAF3 is a critical player.
In comparison to traditional methods, the use of knockout cell lines offers substantial advantages, including greater specificity and reproducibility in experiments. Unlike less precise gene editing methods, CRISPR-based knockouts enable researchers to create models with predictable genetic modifications that are conducive to high-throughput screening and detailed functional analysis.
For researchers, clinicians, and pharmaceutical developers, the BCLAF3 Gene Knockout Cell Lines represent a powerful tool that can accelerate discovery and innovation within the field of genetics and cell biology. By leveraging these advanced models, users can unlock new avenues for research and therapeutic development.
With a commitment to excellence in genetic engineering and a robust portfolio of biological products, our company stands at the forefront of enabling scientific progress, providing researchers with the highest quality cell lines tailored to meet their experimental needs.
Please note that all services are for research use only. Not intended for any clinical use.
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