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BAZ1A Knockout Cell Lines

Gene: BAZ1A

Official Full Name: bromodomain adjacent to zinc finger domain 1Aprovided by HGNC

Gene Summary: The BAZ1A gene encodes the accessory subunit of the ATP-dependent chromatin assembly factor (ACF), a member of the ISWI ('imitation switch') family of chromatin remodeling complexes (summarized by Racki et al., 2009 [PubMed 20033039]).[supplied by OMIM, Apr 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO31120 BAZ1A Knockout cell line (HeLa) Human BAZ1A 1:3~1:6 Negative Online Inquiry
KO31121 BAZ1A Knockout cell line (HCT 116) Human BAZ1A 1:2~1:4 Negative Online Inquiry
KO31122 BAZ1A Knockout cell line (HEK293) Human BAZ1A 1:3~1:6 Negative Online Inquiry
KO31123 BAZ1A Knockout cell line (A549) Human BAZ1A 1:3~1:4 Negative Online Inquiry

Background

BAZ1A Gene Knockout Cell Lines are specifically engineered cellular models that facilitate the exploration of the biological functions of the BAZ1A gene. The BAZ1A gene encodes a protein involved in chromatin remodeling and gene regulation, making its study crucial for understanding various cellular processes, including gene expression, DNA repair, and cell differentiation. Utilizing CRISPR-Cas9 technology, these knockout cell lines have been developed to ensure precise and efficient gene disruption, enabling researchers to analyze the resultant phenotypic changes systematically.

The primary function of BAZ1A Gene Knockout Cell Lines lies in their role as tools for dissecting the biological pathways influenced by the BAZ1A protein. By observing the lack of functionality derived from the gene knockout, researchers can elucidate its contributions to cellular mechanisms and disease states. This is particularly relevant in cancer research, where alterations in chromatin dynamics can lead to aberrant gene expression patterns. The ability to study these knockouts in a controlled environment provides a significant advantage in experimental design, allowing for the development of targeted therapies.

The scientific importance of BAZ1A knockout models extends into clinical applications as well, as insights gained from these studies can drive innovations in therapeutic strategies for disorders linked to chromatin modifications. Their use in drug development and toxicology studies further underscores their versatility in cutting-edge research.

What sets BAZ1A Gene Knockout Cell Lines apart from other models is their reliability, characterized by robust genetic validation and reproducibility. Unlike traditional knockdown methods, a knockout provides a definitive loss-of-function scenario, yielding clearer insights into gene behavior.

For researchers and clinicians interested in gene regulation and its implications in health and disease, BAZ1A Gene Knockout Cell Lines represent an invaluable resource. The precision in gene editing and the ability to generate consistent results greatly enhance the reliability of experimental data.

Our company, with its dedication to advancing biotechnology, offers a portfolio of high-quality biological products designed to support innovative research. Our expertise in genetic engineering ensures that each batch of BAZ1A knockout lines meets stringent quality standards, thus empowering scientists to achieve their research goals effectively.

Please note that all services are for research use only. Not intended for any clinical use.

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