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ASB1 Knockout Cell Lines

Gene: ASB1

Official Full Name: ankyrin repeat and SOCS box containing 1provided by HGNC

Gene Summary: The protein encoded by this gene contains an ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, targeting them for ubiquitination and degradation. [provided by RefSeq, Aug 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22295 ASB1 Knockout cell line (HeLa) Human ASB1 1:3~1:6 Negative Online Inquiry
KO22296 ASB1 Knockout cell line (HCT 116) Human ASB1 1:2~1:4 Negative Online Inquiry
KO22297 ASB1 Knockout cell line (HEK293) Human ASB1 1:3~1:6 Negative Online Inquiry
KO22298 ASB1 Knockout cell line (A549) Human ASB1 1:3~1:4 Negative Online Inquiry

Background

ASB1 Gene Knockout Cell Lines are advanced cellular models designed for the study of the activity and function of the ASB1 gene, a member of the Ankyrin repeat and SOCS box (ASB) family, which plays critical roles in various biological processes, including protein homeostasis, cell signaling, and the regulation of gene expression. These knockout cell lines are engineered using precise gene-editing technologies such as CRISPR/Cas9, which allows for the specific deletion of the ASB1 gene, thereby providing researchers with a powerful tool to investigate the gene's physiological roles and its contribution to disease pathways.

The key mechanism of these cell lines lies in their ability to elucidate the phenotypic consequences of ASB1 gene loss. By comparing the knockout lines to wild-type counterparts, researchers can assess alterations in cellular proliferation, differentiation, and response to stimuli, offering insights into the gene’s involvement in oncogenesis, metabolic disorders, and immune responses. This facilitates research into how dysregulation of ASB1 may contribute to pathologies, thus aiding in the identification of potential therapeutic targets.

The scientific importance of ASB1 Gene Knockout Cell Lines extends to their applications in both basic research and translational medicine. In academic settings, these lines serve as models for pivotal experiments in gene function characterization, while in clinical settings, they provide a foundation for the development of novel treatments and drug discovery. Compared to conventional knockout systems, ASB1 Gene Knockout Cell Lines offer enhanced precision and efficiency, minimizing off-target effects and improving the reliability of experimental outcomes.

One of the most compelling advantages of using ASB1 Gene Knockout Cell Lines is the ability to generate reproducible and consistent results, critical for regulatory compliance in preclinical trials. Their ready-to-use status accelerates the research timeline, enabling faster turnaround for experimental discoveries.

For researchers and clinicians alike, these cell lines are invaluable assets that enhance understanding of gene functionality within the context of human health and disease. By utilizing our ASB1 Gene Knockout Cell Lines, you are tapping into a resource that not only simplifies research but also complements our broader portfolio of innovative biological products designed for cutting-edge research applications. With a commitment to scientific excellence, our company stands at the forefront of biological research tools, empowering investigators to drive breakthroughs in genetics and cell biology.

Please note that all services are for research use only. Not intended for any clinical use.

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