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ARL14EP Knockout Cell Lines

Gene: ARL14EP

Official Full Name: ARF like GTPase 14 effector proteinprovided by HGNC

Gene Summary: The protein encoded by this gene is an effector protein. It interacts with ADP-ribosylation factor-like 14 [ARL14, also known as ADP-ribosylation factor 7 (ARF7)], beta-actin (ACTB) and actin-based motor protein myosin 1E (MYO1E). ARL14 is a small GTPase; it controls the export of major histocompatibility class II molecules by connecting to the actin network via this effector protein. [provided by RefSeq, Sep 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30328 ARL14EP Knockout cell line (HeLa) Human ARL14EP 1:3~1:6 Negative Online Inquiry
KO30329 ARL14EP Knockout cell line (HCT 116) Human ARL14EP 1:2~1:4 Negative Online Inquiry
KO30330 ARL14EP Knockout cell line (HEK293) Human ARL14EP 1:3~1:6 Negative Online Inquiry
KO30331 ARL14EP Knockout cell line (A549) Human ARL14EP 1:3~1:4 Negative Online Inquiry

Background

ARL14EP Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to lack the ARL14EP gene, which encodes a member of the Arf-like small GTPase family known for its regulatory roles in various cellular processes, including cytoskeletal dynamics and vesicle trafficking. These cell lines serve as invaluable tools for researchers investigating the specific functions of ARL14EP in both health and disease contexts. They allow for the dissection of molecular pathways influenced by ARL14EP, facilitating a deeper understanding of its role in cellular signaling and potential involvement in pathological conditions.

The primary mechanism by which these knockout cell lines operate revolves around the disruption of ARL14EP signaling pathways, leading to altered cellular behaviors often linked to proliferation, differentiation, and migration. Studies using these cell lines can elucidate the gene's contribution to tumorigenesis or its potential role in neurodevelopmental disorders, thereby offering insights into therapeutic targets.

The scientific importance of ARL14EP Gene Knockout Cell Lines cannot be overstated; they provide a controlled environment to study gene function, making them ideal for high-throughput screening applications, drug discovery initiatives, and functional genomics studies. Their use could significantly accelerate the pace of research findings and enhance our understanding of ARL14EP in various biological contexts.

Compared to traditional methods of gene silencing, such as RNA interference, gene knockout models offer a more definitive validation of gene function due to the complete absence of the gene product. This specificity empowers researchers to draw clearer conclusions regarding the physiological effects resulting from the gene's loss of function.

For researchers and clinicians seeking to explore the complexities of gene function in a precise manner, ARL14EP Gene Knockout Cell Lines represent a significant advancement. The ability to study the implications of the ARL14EP gene in a controlled, replicable framework enhances the potential for novel discoveries and therapeutic innovations.

As a product of our extensive expertise in genetic engineering and cellular biology, we at [Company Name] are committed to providing high-quality, reliable biological products that meet the evolving needs of the scientific community. Our robust portfolio, including the ARL14EP Gene Knockout Cell Lines, stands as a testament to our dedication to advancing research and improving health outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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