Gene: AREL1
Official Full Name: apoptosis resistant E3 ubiquitin protein ligase 1provided by HGNC
Gene Summary: Enables ubiquitin protein ligase activity. Involved in negative regulation of apoptotic process; protein polyubiquitination; and ubiquitin-dependent protein catabolic process. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO32607 | AREL1 Knockout cell line (HeLa) | Human | AREL1 | 1:3~1:6 | Negative | Online Inquiry |
KO32608 | AREL1 Knockout cell line (HCT 116) | Human | AREL1 | 1:2~1:4 | Negative | Online Inquiry |
KO32609 | AREL1 Knockout cell line (HEK293) | Human | AREL1 | 1:3~1:6 | Negative | Online Inquiry |
KO32610 | AREL1 Knockout cell line (A549) | Human | AREL1 | 1:3~1:4 | Negative | Online Inquiry |
AREL1 Gene Knockout Cell Lines are sophisticated biological tools designed to facilitate the study of the AREL1 gene's role in cellular functions and disease mechanisms. These cell lines have undergone precise genetic modification through CRISPR/Cas9 technology, allowing for the targeted disruption of the AREL1 gene, effectively creating a model to investigate the gene's specific contributions in vitro.
The primary function of AREL1 gene knockout cell lines is to elucidate the biological pathways influenced by AREL1, which is involved in cellular processes such as apoptosis, cell cycle regulation, and transcriptional control. By comparing the knockout versions with wild-type cell lines, researchers can better understand the functional impact of AREL1 deficiency on cellular behavior, gene expression profiles, and response to various stressors or treatments. This makes these cell lines invaluable in cancer research, neurobiology, and developmental studies where AREL1's role is suspected.
Scientifically, the applications of AREL1 gene knockout cell lines are extensive, encompassing basic research, drug discovery, and therapeutic development. In clinical settings, these cell lines can serve as a platform for testing new pharmacological compounds designed to restore normal pathways disrupted by AREL1 mutations, providing insights into potential treatment options for associated diseases.
What sets our AREL1 gene knockout cell lines apart is their robust genetic integrity and reproducibility, which are often issues with alternative models such as transient knockdowns or traditional knockout methods. Our cell lines are extensively validated and characterized, ensuring high specificity and consistent performance across experiments.
For researchers and clinicians seeking to explore gene function and interaction comprehensively, AREL1 gene knockout cell lines present a reliable, advanced tool that can yield high-quality data. Our commitment to providing excelling biological products is backed by our team's expertise in gene editing technologies and extensive experience in the life sciences sector, ensuring that our offerings support and enhance your research endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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