Gene: AP5B1
Official Full Name: adaptor related protein complex 5 subunit beta 1provided by HGNC
Gene Summary: Involved in endosomal transport. Located in lysosomal membrane. Part of AP-type membrane coat adaptor complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23562 | AP5B1 Knockout cell line (HeLa) | Human | AP5B1 | 1:3~1:6 | Negative | Online Inquiry |
KO23563 | AP5B1 Knockout cell line (HCT 116) | Human | AP5B1 | 1:2~1:4 | Negative | Online Inquiry |
KO23564 | AP5B1 Knockout cell line (HEK293) | Human | AP5B1 | 1:3~1:6 | Negative | Online Inquiry |
KO23565 | AP5B1 Knockout cell line (A549) | Human | AP5B1 | 1:3~1:4 | Negative | Online Inquiry |
AP5B1 Gene Knockout Cell Lines are precisely engineered model systems developed to study the role of the AP5B1 gene in various biological processes. These cell lines are generated using advanced CRISPR-Cas9 technology, resulting in the complete inactivation of the AP5B1 gene. The knockout mechanism involves the introduction of targeted double-strand breaks followed by non-homologous end joining, leading to mutations that disrupt the gene’s normal function. This innovative approach enables researchers to dissect the gene's contributions to cellular signaling, disease mechanisms, and potential therapeutic targets.
The scientific significance of AP5B1 knockout cell lines lies in their diverse applications in molecular biology, genetics, and pharmacology. Researchers can utilize these cell lines to examine the effects of AP5B1 deficiency on cellular behavior, metabolic pathways, and responses to drugs. Moreover, this model is instrumental in identifying novel biomarkers and potential interventions for disorders associated with AP5B1 dysregulation, such as neurodegenerative diseases and certain types of cancer.
What sets AP5B1 Gene Knockout Cell Lines apart from alternative models is the specificity and efficiency of the knockout process, coupled with their reproducibility, which ensures consistent experimental outcomes. Unlike traditional knockout models, these cell lines provide a rapid and cost-effective solution for researchers looking to explore gene function without the time-consuming animal model development.
For researchers and clinicians, the value proposition of AP5B1 knockouts is compelling. They streamline experimental workflows, reduce the variability seen in vivo models, and offer insights that can propel research forward, shaping future therapeutic strategies. Our company is committed to advancing scientific research, backed by years of expertise in developing high-quality biological products that empower discovery and innovation in the life sciences sector.
Please note that all services are for research use only. Not intended for any clinical use.
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