Gene: ANKRD42
Official Full Name: ankyrin repeat domain 42provided by HGNC
Gene Summary: Predicted to enable NF-kappaB binding activity. Predicted to act upstream of or within positive regulation of NF-kappaB transcription factor activity and positive regulation of cytokine production involved in inflammatory response. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19824 | ANKRD42 Knockout cell line (HeLa) | Human | ANKRD42 | 1:3~1:6 | Negative | Online Inquiry |
KO19825 | ANKRD42 Knockout cell line (HCT 116) | Human | ANKRD42 | 1:2~1:4 | Negative | Online Inquiry |
KO19826 | ANKRD42 Knockout cell line (HEK293) | Human | ANKRD42 | 1:3~1:6 | Negative | Online Inquiry |
KO19827 | ANKRD42 Knockout cell line (A549) | Human | ANKRD42 | 1:3~1:4 | Negative | Online Inquiry |
ANKRD42 Gene Knockout Cell Lines are specifically engineered cell lines that exhibit a complete absence of the ANKRD42 gene, which plays a critical role in various cellular processes, including cellular signaling and cytoskeletal organization. By employing CRISPR-Cas9 technology, these cell lines facilitate the investigation of gene function, allowing researchers to unravel the complexities of cellular mechanisms underpinned by ANKRD42.
The key functions of ANKRD42 in maintaining cellular integrity and its involvement in pathophysiological conditions underscore the utility of these knockout lines. Researchers can examine the impact of ANKRD42 loss on various signaling pathways, cellular proliferation, and migration, thereby providing insights into potential therapeutic targets for diseases such as cancer and neurodegenerative disorders. Moreover, these cell lines serve as an invaluable tool in pharmacological screenings and gene therapy development, where modulation of ANKRD42 expression may lead to novel treatment approaches.
The scientific importance of using ANKRD42 Gene Knockout Cell Lines extends beyond basic research; they have profound implications for clinical applications, particularly in personalized medicine. By elucidating the role of ANKRD42 in disease contexts, these models can pave the way for biomarker discovery and the development of targeted therapies.
Compared to traditional models, ANKRD42 knockout cell lines offer a higher degree of specificity and control, enabling replicable and robust results that are essential for advancing research. Their streamlined generation process reduces turnaround times, allowing researchers to focus on their studies rather than model development.
This product is an indispensable asset for researchers and clinicians looking to deepen their understanding of ANKRD42-associated pathways. With our expertise in genetic manipulation and cell line development, we are committed to providing top-quality biological products that meet the diverse needs of the scientific community, ensuring that our customers have the best tools at their disposal for groundbreaking research and clinical advancements.
Please note that all services are for research use only. Not intended for any clinical use.
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