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ANKRA2 Knockout Cell Lines

Gene: ANKRA2

Official Full Name: ankyrin repeat family A member 2provided by HGNC

Gene Summary: Enables enzyme binding activity and low-density lipoprotein particle receptor binding activity. Involved in regulation of protein-containing complex assembly. Located in 3M complex; cytosol; and membrane. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20356 ANKRA2 Knockout cell line (HeLa) Human ANKRA2 1:3~1:6 Negative Online Inquiry
KO20357 ANKRA2 Knockout cell line (HCT 116) Human ANKRA2 1:2~1:4 Negative Online Inquiry
KO20358 ANKRA2 Knockout cell line (HEK293) Human ANKRA2 1:3~1:6 Negative Online Inquiry
KO20359 ANKRA2 Knockout cell line (A549) Human ANKRA2 1:3~1:4 Negative Online Inquiry

Background

ANKRA2 Gene Knockout Cell Lines are genetically engineered cells specifically designed to lack the ANKRA2 gene, which encodes a protein implicated in various cellular processes, including gene regulation and cellular stress responses. By selectively disrupting this gene, these cell lines serve as a powerful tool for elucidating the role of ANKRA2 in biological pathways and disease mechanisms. Utilizing CRISPR-Cas9 gene-editing technology, the construction of these knockout lines provides researchers with a precise and efficient means to study the functional consequences of gene loss.

The key function of ANKRA2 Gene Knockout Cell Lines lies in their ability to facilitate detailed investigations of ANKRA2's involvement in cellular signaling, differentiation, and response to environmental stressors. These models can be invaluable for exploring the molecular underpinnings of diseases such as cancer, neurodegeneration, and metabolic disorders. By providing a clear comparison to wild-type controls, researchers can gain insights into gene-dependent cellular behaviors and identify potential targets for therapeutic intervention.

In clinical and research settings, the importance of ANKRA2 knockout models cannot be overstated. They allow for the identification of compensatory mechanisms that may arise due to the loss of the gene, thus paving the way for the development of novel therapeutic strategies. Moreover, these cell lines offer a reproducible platform for high-throughput screening of compounds that may interact with the ANKRA2 pathway.

Compared to alternative models, the ANKRA2 Gene Knockout Cell Lines provide several distinct advantages. These include the precision of gene deletion, reduced off-target effects, and accessibility to a broad array of assays and applications, from basic research to drug discovery. By enabling researchers to directly manipulate genetic expression, these cell lines represent a significant advancement in functional genomics.

For researchers, clinicians, and pharmaceutical developers, the ANKRA2 Gene Knockout Cell Lines are invaluable assets that can drive innovation in biological research and drug development. Our company's commitment to quality and excellence underpins our expertise in providing reliable and scientifically robust biological products that enhance research capabilities and promote breakthroughs in health sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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