Gene: ANKFY1
Official Full Name: ankyrin repeat and FYVE domain containing 1provided by HGNC
Gene Summary: This gene encodes a cytoplasmic protein that contains a coiled-coil structure and a BTB/POZ domain at its N-terminus, ankyrin repeats in the middle portion, and a FYVE-finger motif at its C-terminus. This protein belongs to a subgroup of double zinc finger proteins which may be involved in vesicle or protein transport. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, Apr 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO22497 | ANKFY1 Knockout cell line (HeLa) | Human | ANKFY1 | 1:3~1:6 | Negative | Online Inquiry |
KO22498 | ANKFY1 Knockout cell line (HCT 116) | Human | ANKFY1 | 1:2~1:4 | Negative | Online Inquiry |
KO22499 | ANKFY1 Knockout cell line (HEK293) | Human | ANKFY1 | 1:3~1:6 | Negative | Online Inquiry |
KO22500 | ANKFY1 Knockout cell line (A549) | Human | ANKFY1 | 1:3~1:4 | Negative | Online Inquiry |
ANKFY1 Gene Knockout Cell Lines are genetically engineered cellular models that provide a robust platform for studying the function of the ANKFY1 gene. The ANKFY1 (Ankyrin Repeat and FYVE Domain Containing 1) gene is implicated in various cellular processes, including endosomal transport, protein interactions, and signal transduction pathways. By creating knockout models, researchers can observe the phenotypic consequences resulting from the absence of the ANKFY1 protein, allowing for an in-depth analysis of its specific roles in cellular dynamics.
The cell lines function by utilizing CRISPR-Cas9 technology, a precise and efficient gene editing method that introduces targeted mutations in the ANKFY1 gene, leading to a complete loss of function. This enables scientists to dissect the biochemical pathways influenced by ANKFY1 and its contribution to various diseases, including cancer and metabolic disorders. By employing these knockout cell lines, researchers can innovate new therapeutic strategies and explore disease mechanisms at a cellular level.
The scientific importance of ANKFY1 Gene Knockout Cell Lines extends to their applications in both basic research and clinical settings. They serve as valuable tools for drug discovery, allowing for high-throughput screening to identify potential therapeutics that may interact with the pathways involving ANKFY1. Additionally, these cell lines help elucidate gene-environment interactions that can inform personalized medicine approaches.
Compared to alternative cell models, ANKFY1 Gene Knockout Cell Lines offer unparalleled specificity in evaluating the loss of ANKFY1 function without the confounding effects observed in partial knockdowns or wild-type systems. They provide a reliable and reproducible platform that ensures consistent results across experiments.
For researchers and clinicians, ANKFY1 Gene Knockout Cell Lines present an invaluable opportunity to advance understanding in the field of molecular biology and to contribute to the development of targeted therapies. With a dedicated focus on quality and innovation, our company stands as a leader in the production of specialized genetic models, empowering researchers to accelerate their findings and enhance translational science.
Please note that all services are for research use only. Not intended for any clinical use.
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