Gene: AMN1
Official Full Name: antagonist of mitotic exit network 1 homologprovided by HGNC
Gene Summary: Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. Predicted to be active in microvillus membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19875 | AMN1 Knockout cell line (HeLa) | Human | AMN1 | 1:3~1:6 | Negative | Online Inquiry |
KO19876 | AMN1 Knockout cell line (HCT 116) | Human | AMN1 | 1:2~1:4 | Negative | Online Inquiry |
KO19877 | AMN1 Knockout cell line (HEK293) | Human | AMN1 | 1:3~1:6 | Negative | Online Inquiry |
KO19878 | AMN1 Knockout cell line (A549) | Human | AMN1 | 1:3~1:4 | Negative | Online Inquiry |
AMN1 Gene Knockout Cell Lines are genetically engineered cellular models designed to specifically silence the AMN1 gene, which is involved in the regulation of cellular processes such as cell division and differentiation. These cell lines utilize CRISPR/Cas9 technology to create targeted deletions within the AMN1 gene, allowing researchers to elucidate its functional role in various biological pathways. By removing the expression of AMN1, users can study downstream effects on cellular behavior, signaling pathways, and gene interactions, making these cell lines invaluable for both basic and applied biological research.
The primary function of AMN1 Gene Knockout Cell Lines is to facilitate the examination of gene function and its implications in cellular phenotypes. By providing a model system that mimics the absence of AMN1, researchers can explore the gene's contribution to cellular processes, disease mechanisms, and potential therapeutic targets. This mechanism not only accelerates research into cellular dynamics but also aids in the identification of new biomarkers or drug candidates in oncology and other fields.
Scientifically, these knockout cell lines are pivotal for advancing our understanding of gene function in both research and clinical settings. They allow for high-throughput drug screening, validation of gene targets, and assessment of the effects of genetic aberrations in disease models. Moreover, utilizing such sophisticated models can enhance the credibility of research findings, as they provide a closer approximation to in vivo biological processes.
Compared to conventional gene knockdown methods, AMN1 Gene Knockout Cell Lines offer significant advantages. The CRISPR/Cas9 technique provides a more precise and efficient means of creating stable genetic modifications, leading to better reproducibility of results. Additionally, these cell lines come with extensive characterization data, ensuring researchers can trust the integrity and reliability of their experiments.
The value of AMN1 Gene Knockout Cell Lines lies in their potential to catalyze groundbreaking insights in the biological sciences. Researchers and clinicians can leverage these tools to advance their understanding of genetic regulation and pathology, ultimately leading to the development of innovative therapeutic strategies.
Our company prides itself on its expertise in producing high-quality, customized biological products suited to meet the needs of researchers and clinicians. We are committed to enabling scientific discovery through robust and reliable models that empower innovation across various fields of study.
Please note that all services are for research use only. Not intended for any clinical use.
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