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ALPK2 Knockout Cell Lines

Gene: ALPK2

Official Full Name: alpha kinase 2provided by HGNC

Gene Summary: Predicted to enable ATP binding activity; protein serine kinase activity; and protein serine/threonine kinase activity. Involved in several processes, including epicardium morphogenesis; heart development; and negative regulation of Wnt signaling pathway involved in heart development. Acts upstream of or within regulation of gene expression. Located in basolateral plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO03234 ALPK2 Knockout cell line (HeLa) Human ALPK2 1:3~1:6 Negative Online Inquiry
KO03235 ALPK2 Knockout cell line (A549) Human ALPK2 1:3~1:4 Negative Online Inquiry

Background

ALPK2 Gene Knockout Cell Lines are specially engineered cell lines in which the ALPK2 gene has been inactivated through targeted gene-editing techniques such as CRISPR-Cas9. The ALPK2 gene encodes a serine/threonine kinase implicated in various cellular processes, including mitotic regulation, signaling pathways, and cell growth. By creating knockout variants, researchers can investigate the specific functions of ALPK2, allowing for a better understanding of its role in developmental biology and pathological conditions.

The key function of ALPK2 Gene Knockout Cell Lines lies in their ability to elucidate the biological pathways influenced by the ALPK2 protein. Through these models, researchers can study the molecular mechanisms leading to alterations in cell cycle progression and metabolic reactions, as well as responses to external stimuli. This makes the knockout cell lines invaluable tools for exploring the gene's contributions to diseases such as cancer and metabolic disorders.

The scientific importance of these cell lines cannot be understated; they serve as crucial resources for both fundamental research and drug development initiatives. They enable the testing of various pharmaceuticals and therapeutic interventions, providing insight into potential treatment pathways targeting the ALPK2 gene and its associated signaling networks. In clinical settings, understanding these pathways can also lead to the identification of biomarkers for disease progression, aiding in the development of personalized medicine strategies.

Compared to alternative gene editing approaches, ALPK2 Gene Knockout Cell Lines stand out due to their specificity and accuracy, allowing for precise characterization of the ALPK2 gene's role without the off-target effects often associated with less targeted methods. Additionally, these knockout cell lines are ready-to-use, saving researchers valuable time and resources in their experimental design.

For researchers and clinicians focused on genetic and molecular research, employing ALPK2 Gene Knockout Cell Lines enhances experimental rigor and provides unique insights into complex biological questions. These cell lines not only facilitate advancements in basic research but also foster the discovery of therapeutic strategies that could transform patient outcomes.

Our company prides itself on delivering high-quality biological products supported by extensive expertise in genetic engineering and cell line development. We are committed to advancing scientific research and innovation, offering products that empower the research community to achieve their scientific objectives effectively.

Please note that all services are for research use only. Not intended for any clinical use.

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