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ALOX12B Knockout Cell Lines

Gene: ALOX12B

Official Full Name: arachidonate 12-lipoxygenase, 12R typeprovided by HGNC

Gene Summary: This gene encodes an enzyme involved in the conversion of arachidonic acid to 12R-hydroxyeicosatetraenoic acid. Mutations in this gene are associated with nonbullous congenital ichthyosiform erythroderma. [provided by RefSeq, Sep 2015]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO39026 ALOX12B Knockout cell line (HCT 116) Human ALOX12B 1:2~1:4 Negative Online Inquiry
KO39027 ALOX12B Knockout cell line (HEK293) Human ALOX12B 1:3~1:6 Negative Online Inquiry

Background

ALOX12B Gene Knockout Cell Lines represent a cutting-edge tool in genetic research, specifically designed to investigate the role of the ALOX12B gene in various biological processes. This product consists of genetically modified cell lines in which the ALOX12B gene has been selectively disrupted using CRISPR-Cas9 technology, allowing scientists to analyze gene function and related pathways in a controlled environment.

The key function of ALOX12B is its role in the metabolism of omega-6 fatty acids and the synthesis of bioactive lipid mediators. By knocking out this gene, researchers can explore its contribution to inflammation, skin barrier functions, and other physiological processes. The precise knockout mechanism enables the elucidation of the functional consequences of ALOX12B deficiency, providing valuable insights into its involvement in diseases such as atherosclerosis and psoriasis.

The scientific importance of ALOX12B Knockout Cell Lines lies not only in their utility for fundamental biology but also in their applicability to clinical research. These cell lines can serve as experimental models for drug discovery and the testing of therapeutic interventions that target lipid metabolism. Moreover, these models can aid in the development of personalized medicine approaches by offering a platform for studying patient-derived cells with specific genetic backgrounds.

What sets our ALOX12B Gene Knockout Cell Lines apart from alternatives is their robust validation, ensuring high specificity and reproducibility in experimental results. Each line is rigorously characterized to confirm the knockout efficiency and is supplied with detailed protocols and support, enabling researchers to achieve optimal outcomes in their studies.

For researchers and clinicians, the value of ALOX12B Gene Knockout Cell Lines is substantial; they not only reduce the time required for experimental setup but also enhance the reliability of data generated, thereby accelerating scientific discovery. In addition, our company boasts extensive expertise in genetic engineering and cell line development, ensuring that our products meet the highest standards of quality and performance. By providing reliable tools like the ALOX12B Gene Knockout Cell Lines, we empower researchers to push the boundaries of scientific inquiry and unlock new therapeutic avenues.

Please note that all services are for research use only. Not intended for any clinical use.

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