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AKR7A3 Knockout Cell Lines

Gene: AKR7A3

Official Full Name: aldo-keto reductase family 7 member A3provided by HGNC

Gene Summary: Aldo-keto reductases, such as AKR7A3, are involved in the detoxification of aldehydes and ketones.[supplied by OMIM, Apr 2004]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30080 AKR7A3 Knockout cell line (HCT 116) Human AKR7A3 1:2~1:4 Negative Online Inquiry

Background

AKR7A3 Gene Knockout Cell Lines are specially engineered cellular models designed to study the biological role of the AKR7A3 gene, which has been implicated in various metabolic pathways and disease states, including cancer and metabolic disorders. By utilizing CRISPR-Cas9 technology, these cell lines exhibit precise disruptions in the AKR7A3 gene, allowing researchers to investigate the consequent phenotypic and biochemical effects directly.

The primary function of AKR7A3 Gene Knockout Cell Lines involves elucidating the gene's contribution to biological processes, including its potential role in detoxifying reactive aldehydes and contributing to cellular oxidative stress responses. Through a series of assays such as proliferation, migration, and metabolic profiling, researchers can uncover the regulatory mechanisms and pathways influenced by AKR7A3 knockout, thus advancing our understanding of its function in health and disease.

The scientific importance of these cell lines in both research and clinical settings cannot be overstated. They provide a vital in vitro tool for investigating drug responses, mechanisms of resistance, and potential therapeutic targets, especially in oncology and metabolic research. By understanding the ramifications of AKR7A3 loss, researchers can better develop novel therapeutic strategies and prognostic biomarkers.

Distinct from other knockout models, the AKR7A3 Gene Knockout Cell Lines offer unparalleled specificity and reproducibility, ensuring that results are reliable and easily interpreted. The ability to create multiple clones with varying degrees of gene disruption allows for a comprehensive analysis of dose-response relationships in drug discovery.

For researchers and clinicians, these cell lines represent a valuable asset in the pursuit of groundbreaking discoveries. They facilitate deeper insights into the molecular underpinnings of disease, fostering the development of innovative therapeutic approaches that could ultimately lead to improved patient outcomes.

With a commitment to advancing biological research, our company excels in developing high-quality cellular models that support a wide range of scientific inquiries. Our expertise ensures that researchers have access to the most reliable tools for uncovering the complexities of gene function in health and disease.

Please note that all services are for research use only. Not intended for any clinical use.

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