Gene: AFAP1
Official Full Name: actin filament associated protein 1provided by HGNC
Gene Summary: The protein encoded by this gene is a Src binding partner. It may represent a potential modulator of actin filament integrity in response to cellular signals, and may function as an adaptor protein by linking Src family members and/or other signaling proteins to actin filaments. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19961 | AFAP1 Knockout cell line (HeLa) | Human | AFAP1 | 1:3~1:6 | Negative | Online Inquiry |
KO19962 | AFAP1 Knockout cell line (HCT 116) | Human | AFAP1 | 1:2~1:4 | Negative | Online Inquiry |
KO19963 | AFAP1 Knockout cell line (HEK293) | Human | AFAP1 | 1:3~1:6 | Negative | Online Inquiry |
KO19964 | AFAP1 Knockout cell line (A549) | Human | AFAP1 | 1:3~1:4 | Negative | Online Inquiry |
AFAP1 Gene Knockout Cell Lines are genetically engineered cell models designed to specifically deactivate the AFAP1 gene, which encodes for the actin filament-associated protein 1. This innovative product enables researchers to study the role of AFAP1 in various cellular processes, including signaling pathways, cell motility, and cytoskeletal dynamics, through the direct observation of its absence in a controlled environment.
The key function of these knockout cell lines is to facilitate investigations into the physiological and pathological implications of AFAP1 deficiency. By using CRISPR-Cas9 technology or similar gene-editing strategies, these cell lines provide an unprecedented opportunity to explore the mechanisms by which AFAP1 influences cellular behavior and its potential impact on disease states, such as cancer metastasis and myocardial infarction. This research tool allows for a detailed examination of downstream effects on gene expression and cellular morphology, leading to a deeper understanding of AFAP1’s biological significance.
Scientifically, the AFAP1 Gene Knockout Cell Lines hold immense value in both research and clinical applications. They serve as pivotal models for drug discovery, toxicology studies, and functional assays that may elucidate therapeutic targets for diseases associated with AFAP1 dysregulation. Furthermore, they enable researchers to test the efficacy of novel compounds and screen for potential side effects on cell behavior in a relevant biological context.
Compared to standard wild-type cell lines, the AFAP1 Gene Knockout Cell Lines offer a clear advantage by providing an isogenic system for the study of gene function without the confounding effects of genetic variation. This specificity enhances experimental reproducibility and accuracy, making findings more reliable and facilitating the advancement of translational research.
For researchers and clinicians, the value of utilizing AFAP1 Gene Knockout Cell Lines lies in their ability to generate insights that can lead to novel therapeutic approaches or biomarker discoveries. By elucidating the complex roles of AFAP1 in health and disease, these cell lines are instrumental in bridging the gap between basic science and clinical application.
Our company is committed to advancing scientific research through high-quality, genetically modified cell lines. With expertise in genetic engineering and a focus on innovation, we strive to provide researchers with cutting-edge tools that enhance their ability to uncover the secrets of biological systems and develop impactful therapies.
Please note that all services are for research use only. Not intended for any clinical use.
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