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ADSS2 Knockout Cell Lines

Gene: ADSS2

Official Full Name: adenylosuccinate synthase 2provided by HGNC

Gene Summary: This gene encodes the enzyme adenylosuccinate synthetase which catalyzes the first committed step in the conversion of inosine monophosphate to adenosine monophosphate. A pseudogene of this gene is found on chromosome 17.[provided by RefSeq, Nov 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO39092 ADSS2 Knockout cell line (HeLa) Human ADSS2 1:3~1:6 Negative Online Inquiry
KO39093 ADSS2 Knockout cell line (HCT 116) Human ADSS2 1:2~1:4 Negative Online Inquiry
KO39094 ADSS2 Knockout cell line (HEK293) Human ADSS2 1:3~1:6 Negative Online Inquiry
KO39095 ADSS2 Knockout cell line (A549) Human ADSS2 1:3~1:4 Negative Online Inquiry

Background

ADSS2 Gene Knockout Cell Lines are genetically engineered cell lines designed to facilitate the study of the ADSS2 gene and its associated biological pathways. By employing CRISPR-Cas9 technology, these cell lines feature specific deletions in the ADSS2 gene, effectively creating a knockout model that allows researchers to investigate gene function and its implications in cellular metabolism and disease mechanisms.

The primary function of the ADSS2 Gene Knockout Cell Lines is to provide a platform for the detailed investigation of purine nucleotide synthesis and related metabolic pathways. Through the absence of ADSS2 expression, researchers can examine alterations in adenine metabolism, cellular proliferation, and signaling pathways, enabling insights into the roles of this gene in various physiological and pathological contexts. Moreover, these knockout cell lines can serve as pivotal tools in drug discovery and therapeutic intervention studies targeting metabolic disorders or cancer, where ADSS2 activity may play a critical role.

In scientific research and clinical applications, the importance of ADSS2 Gene Knockout Cell Lines cannot be overstated. Their utility extends to understanding the pathophysiology of diseases like certain types of cancer, where altered purine metabolism is implicated. Researchers can use these cell lines to explore gene interactions, perform high-throughput screening of pharmacological agents, and evaluate gene therapy strategies.

Compared to conventional methods of gene knockout, these cell lines offer superior precision, consistency, and reproducibility, thereby enhancing the reliability of experimental outcomes. They also eliminate the time-consuming and often inconsistent process of generating stable knockout clones through traditional transfection methods. This streamlined approach allows for quicker turnaround times on experiments and reliable data generation, setting ADSS2 Gene Knockout Cell Lines apart in the market.

For researchers and clinicians alike, the value of these knockout cell lines lies in their ability to provide insights into critical biological pathways, facilitating breakthroughs in understanding complex diseases. Our company specializes in advanced genetic engineering techniques and is committed to supporting the global research community with high-quality biological products designed for impactful scientific exploration.

Please note that all services are for research use only. Not intended for any clinical use.

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