Gene: ADGRA3
Official Full Name: adhesion G protein-coupled receptor A3provided by HGNC
Gene Summary: This gene encodes a member of the G protein-coupled receptor superfamily. This membrane protein may play a role in tumor angiogenesis through its interaction with the human homolog of the Drosophila disc large tumor suppressor gene. This gene is mapped to a candidate region of chromosome 4 which may be associated with bipolar disorder and schizophrenia. [provided by RefSeq, Oct 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19988 | ADGRA3 Knockout cell line (HeLa) | Human | ADGRA3 | 1:3~1:6 | Negative | Online Inquiry |
KO19989 | ADGRA3 Knockout cell line (HCT 116) | Human | ADGRA3 | 1:2~1:4 | Negative | Online Inquiry |
KO19990 | ADGRA3 Knockout cell line (HEK293) | Human | ADGRA3 | 1:3~1:6 | Negative | Online Inquiry |
KO19991 | ADGRA3 Knockout cell line (A549) | Human | ADGRA3 | 1:3~1:4 | Negative | Online Inquiry |
ADGRA3 Gene Knockout Cell Lines are specialized laboratory tools designed for the targeted deletion of the ADGRA3 gene, which encodes for a G protein-coupled receptor implicated in several physiological processes, including immune responses and tissue homeostasis. These cell lines serve as vital resources for researchers investigating the gene's role in pathophysiology, such as cancer and inflammatory diseases.
The functionality of ADGRA3 Gene Knockout Cell Lines hinges on advanced CRISPR-Cas9 gene editing technology, which allows for precise genomic modifications. By knocking out the ADGRA3 gene, researchers can elucidate its biological functions and interactions, providing insights into signaling pathways and cellular mechanisms that may contribute to disease manifestation and progression. This precision enables the assessment of phenotypic changes that occur in the absence of ADGRA3, accelerating our understanding of its physiological and pathological roles.
The scientific importance of these cell lines extends into both research and clinical applications. They are invaluable for drug discovery, biomarker identification, and functional studies that aim to validate therapeutic targets. Understanding the ADGRA3 gene's contributions can lead to innovative treatment strategies for various diseases, thus highlighting their clinical relevance.
Compared to existing cell line models, ADGRA3 Gene Knockout Cell Lines offer unmatched specificity and control over genetic variables, circumventing the limitations associated with traditional knockdown approaches. Additionally, the resilience of these cell lines to culture conditions maximizes their utility in diverse experimental settings, making them an unparalleled choice for researchers aiming to dissect complex biological systems.
For researchers and clinicians alike, the value of ADGRA3 Gene Knockout Cell Lines is evident in their ability to drive significant scientific advancements and therapeutic innovations. By leveraging these cell lines, users can gain critical insights that are integral to the development of novel therapies.
Our company, with years of expertise in producing high-quality biological research tools, is committed to providing researchers with state-of-the-art cell line solutions. We continually strive to push the boundaries of scientific discovery, ensuring our customers have access to the most reliable and innovative products in the field.
Please note that all services are for research use only. Not intended for any clinical use.
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