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ADAM32 Knockout Cell Lines

Gene: ADAM32

Official Full Name: ADAM metallopeptidase domain 32provided by HGNC

Gene Summary: This gene encodes a member of the disintegrin family of membrane-anchored proteins that play a role in diverse biological processes such as brain development, fertilization, tumor development and inflammation. This gene is predominantly expressed in the testis. The encoded protein undergoes proteolytic processing to generate a mature polypeptide comprised of an metalloprotease, disintegrin and epidermal growth factor-like domains. This gene is located in a cluster of other disintegrin and metallopeptidase family genes on chromosome 8. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO36168 ADAM32 Knockout cell line (HeLa) Human ADAM32 1:3~1:6 Negative Online Inquiry
KO36169 ADAM32 Knockout cell line (HCT 116) Human ADAM32 1:2~1:4 Negative Online Inquiry
KO36170 ADAM32 Knockout cell line (A549) Human ADAM32 1:3~1:4 Negative Online Inquiry

Background

ADAM32 Gene Knockout Cell Lines are a revolutionary tool designed for researchers seeking to investigate the biological functions of the ADAM32 gene, which encodes a member of the ADAM (A Disintegrin and Metalloproteinase) family of proteins. These cell lines have been genetically modified to inhibit ADAM32 expression, allowing for the in-depth exploration of the gene's role in various cellular processes and its implications in pathological conditions, particularly in reproductive biology and potential tumorigenesis.

The key function of ADAM32 Gene Knockout Cell Lines lies in their ability to facilitate the study of the ADAM32 protein’s functions through loss-of-function experiments. By using these knockout models, researchers can delineate the molecular pathways that ADAM32 influences, which may include cell adhesion, migration, and subsequent signaling cascades. This functional insight is crucial for understanding its contribution to fertility, embryonic development, and other related diseases.

Scientifically, the application of ADAM32 Gene Knockout Cell Lines extends into various branches of biomedical research, including cancer therapeutics, reproductive health studies, and the development of regenerative medicine strategies. Their utility in preclinical trials makes them a vital asset for both research institutions and clinical settings, as they provide an essential framework for the evaluation of novel therapeutic approaches targeting ADAM32-related pathways.

What sets ADAM32 Gene Knockout Cell Lines apart from other models is their precise gene-editing technology, which ensures reliable and reproducible results. This specificity not only reduces off-target effects but also streamlines the study of ADAM32 functions compared to more generalized knockdown approaches. Moreover, the availability of these knockout models can significantly accelerate the research timeline, offering researchers the opportunity to generate publishable data more efficiently.

For researchers, clinicians, and biotechnology professionals alike, the ADAM32 Gene Knockout Cell Lines represent an invaluable resource that enhances the understanding of complex biological processes and disease mechanisms. The potential to uncover novel therapeutic targets can lead to groundbreaking advancements in medicine.

Our company prides itself on its expertise in developing innovative biological products that serve the scientific community. With a commitment to quality and precision, we are dedicated to providing you with the tools necessary for pioneering research and discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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