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ACCS Knockout Cell Lines

Gene: ACCS

Official Full Name: 1-aminocyclopropane-1-carboxylate synthase homolog (inactive)provided by HGNC

Gene Summary: Enables identical protein binding activity. Predicted to be involved in amino acid metabolic process. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24723 ACCS Knockout cell line (HeLa) Human ACCS 1:3~1:6 Negative Online Inquiry
KO24724 ACCS Knockout cell line (HCT 116) Human ACCS 1:2~1:4 Negative Online Inquiry
KO24725 ACCS Knockout cell line (HEK293) Human ACCS 1:3~1:6 Negative Online Inquiry
KO24726 ACCS Knockout cell line (A549) Human ACCS 1:3~1:4 Negative Online Inquiry

Background

ACCS Gene Knockout Cell Lines are advanced, genetically engineered cell models specifically designed to enable researchers to study the effects and functions of the Acetyl-CoA Carboxylase (ACCS) gene within various biological contexts. These cell lines are created through the precise application of CRISPR-Cas9 gene editing technology, resulting in the targeted disruption of the ACCS gene, allowing for in-depth analysis of its role in metabolic pathways, lipid biosynthesis, and cellular signaling.

The key functions of ACCS Gene Knockout Cell Lines stem from their ability to mimic specific genetic deficiencies, thus providing a controlled environment where the impact of ACCS loss can be systematically investigated. Researchers can explore changes in metabolic flux, lipid droplet dynamics, and the activation of compensatory pathways, all of which are critical for understanding diseases such as obesity, diabetes, and cancer. Through these studies, insights into the metabolic reprogramming and potential therapeutic targets for intervention arise.

The scientific importance of ACCS Gene Knockout Cell Lines is underscored by their application across multiple research disciplines, including pharmacology, endocrinology, and oncology, enhancing the understanding of metabolic disorders and facilitating drug discovery efforts. Without these models, researchers may struggle to obtain comparable results in wild-type systems, where the ACCS gene may still be influencing the observed biological phenomena.

One of the unique selling points of our ACCS Gene Knockout Cell Lines is their high specificity and reproducibility, contrasted with conventional knockdown methods that can result in incomplete gene silencing or off-target effects. Additionally, these models are generated with the intention of maintaining physiological relevance, which is crucial for experimental fidelity. The availability of such precise tools directly enhances the robustness of experimental outcomes and accelerates the pathway from basic research to clinical application.

For researchers and clinicians alike, ACCS Gene Knockout Cell Lines represent a valuable asset in advancing metabolic research and therapeutic development. By utilizing these advanced cell lines, scientists can more effectively investigate the implications of ACCS-related metabolic pathways, paving the way for novel therapies aimed at metabolic diseases.

Our company prides itself on its expertise in genetic engineering and cell line development, ensuring that we provide high-quality biological models tailored to the exacting needs of the scientific community. Our commitment to innovation and quality positions us as a leader in the field, supporting your research endeavors with cutting-edge products like our ACCS Gene Knockout Cell Lines.

Please note that all services are for research use only. Not intended for any clinical use.

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