Gene: ACAP3
Official Full Name: ArfGAP with coiled-coil, ankyrin repeat and PH domains 3provided by HGNC
Gene Summary: Predicted to enable GTPase activator activity and metal ion binding activity. Predicted to act upstream of or within neuron migration and regulation of neuron projection development. Predicted to be located in endosome membrane and growth cone. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30467 | ACAP3 Knockout cell line (HeLa) | Human | ACAP3 | 1:3~1:6 | Negative | Online Inquiry |
KO30468 | ACAP3 Knockout cell line (HCT 116) | Human | ACAP3 | 1:2~1:4 | Negative | Online Inquiry |
KO30469 | ACAP3 Knockout cell line (HEK293) | Human | ACAP3 | 1:3~1:6 | Negative | Online Inquiry |
KO30470 | ACAP3 Knockout cell line (A549) | Human | ACAP3 | 1:3~1:4 | Negative | Online Inquiry |
ACAP3 Gene Knockout Cell Lines represent a sophisticated tool designed for researchers investigating the roles of the ACAP3 gene in cellular processes and disease mechanisms. These cell lines are genetically modified to disrupt the ACAP3 gene, allowing scientists to study the resultant phenotypic changes and functional aberrations that occur in the absence of this specific gene expression.
The primary mechanism involves the targeted deletion of the ACAP3 gene utilizing CRISPR-Cas9 technology, which enables precise editing of the genome. By inactivating ACAP3, which is involved in regulating endocytosis and protein trafficking, researchers can elucidate the pathway alterations that contribute to various pathologies, including cancer and neurodegenerative diseases. These knockout cell lines provide a controlled environment to assess the functional consequences of ACAP3 loss, offering insights into cellular signaling, growth regulation, and intercellular communication.
From a scientific perspective, the availability of ACAP3 Gene Knockout Cell Lines is crucial for advancing research in both academic and clinical settings. They are invaluable for drug discovery processes, allowing for high-throughput screening of therapeutic agents that target pathways influenced by ACAP3. Furthermore, they aid in the development of personalized medicine approaches by identifying potential biomarkers associated with ACAP3 dysfunction.
Compared to conventional cell lines that express the full repertoire of endogenous genes, ACAP3 knockout lines offer a unique advantage in studying specific biological pathways without the confounding effects of ACAP3 activity. This specificity results in more accurate modeling of diseases that correlate with the gene's dysfunction, establishing a clearer link between genotype and phenotype.
The value of ACAP3 Gene Knockout Cell Lines is profound for researchers and clinicians focused on understanding complex diseases and developing novel therapeutic strategies. By utilizing these advanced tools, users can accelerate discoveries that may lead to significant breakthroughs in treatment and patient outcomes. At [Your Company Name], we pride ourselves on offering high-quality, rigorously validated biological products that empower our clients in their scientific endeavors, showcasing our commitment to excellence in research solutions.
Please note that all services are for research use only. Not intended for any clinical use.
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