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ACAD10 Knockout Cell Lines

Gene: Acad10

Official Full Name: acyl-Coenzyme A dehydrogenase family, member 10provided by MGI

Gene Summary: Predicted to enable acyl-CoA dehydrogenase activity. Predicted to be involved in fatty acid beta-oxidation using acyl-CoA dehydrogenase. Located in mitochondrion. Orthologous to human ACAD10 (acyl-CoA dehydrogenase family member 10). [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO06185 ACAD10 Knockout cell line (HeLa) Human ACAD10 1:3~1:6 Negative Online Inquiry
KO06186 ACAD10 Knockout cell line (HCT 116) Human ACAD10 1:2~1:4 Negative Online Inquiry
KO06187 ACAD10 Knockout cell line (HEK293) Human ACAD10 1:3~1:6 Negative Online Inquiry
KO06188 ACAD10 Knockout cell line (A549) Human ACAD10 1:3~1:4 Negative Online Inquiry

Background

Acad10 Gene Knockout Cell Lines are a specialized set of genetically engineered cell lines designed to provide researchers with a unique tool for studying the biological roles of the Acad10 gene, which encodes an acyl-CoA dehydrogenase that plays a crucial role in lipid metabolism and energy homeostasis. By utilizing CRISPR-Cas9 technology, these cell lines have been precisely modified to lack functional Acad10, allowing for in-depth analysis of gene function and associated metabolic pathways.

The primary function of the Acad10 knockout cell lines lies in their ability to elucidate the effects of Acad10 loss on cellular metabolism, particularly in the context of fatty acid oxidation and energy production. Researchers can investigate compensatory metabolic adaptations, changes in gene expression, and alterations in cellular signaling pathways that occur in response to the absence of this gene. This provides a robust platform for enhancing our understanding of metabolic diseases, such as obesity, diabetes, and cardiovascular conditions.

The scientific importance of Acad10 Gene Knockout Cell Lines extends to both academic and clinical research applications, where they can be employed in drug development, biomarker discovery, and therapeutic intervention studies. They serve as potent models for screening potential treatments targeting lipid metabolism disorders, thereby accelerating the translational aspect of metabolic research.

What sets these cell lines apart from traditional models is their high specificity and reproducibility, which reduce experimental variability and enhance data reliability. Researchers can confidently use Acad10 knockout cells to ensure that observed phenotypic changes are directly attributed to the gene's loss of function, thus streamlining the experimental design.

Academically and clinically valuable, Acad10 Gene Knockout Cell Lines are indispensable for scientists aiming to deepen their understanding of lipid metabolism and its implications in diverse health conditions. By choosing our product, users benefit from the collective expertise of our team in cutting-edge gene editing technologies and our commitment to delivering high-quality biological research tools.

Please note that all services are for research use only. Not intended for any clinical use.

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