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ABHD3 Knockout Cell Lines

Gene: ABHD3

Official Full Name: abhydrolase domain containing 3, phospholipaseprovided by HGNC

Gene Summary: This gene encodes a protein containing an alpha/beta hydrolase fold, which is a catalytic domain found in a very wide range of enzymes. The function of this protein has not been determined. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20086 ABHD3 Knockout cell line (HeLa) Human ABHD3 1:3~1:6 Negative Online Inquiry
KO20087 ABHD3 Knockout cell line (HCT 116) Human ABHD3 1:2~1:4 Negative Online Inquiry
KO20088 ABHD3 Knockout cell line (HEK293) Human ABHD3 1:3~1:6 Negative Online Inquiry
KO20089 ABHD3 Knockout cell line (A549) Human ABHD3 1:3~1:4 Negative Online Inquiry

Background

ABHD3 Gene Knockout Cell Lines are specialized cellular models engineered to have a targeted deletion of the ABHD3 gene, which encodes for the enzyme acyl-biotinyl hydrolase. This enzyme plays a critical role in lipid metabolism and signaling pathways, making it a significant focus in cellular and molecular biology studies. By utilizing CRISPR/Cas9 technology or similar gene-editing techniques, these cell lines provide researchers with a powerful tool to elucidate the functions of ABHD3 and its implications in various biological processes, including inflammation, neurobiology, and metabolic disorders.

The primary function of ABHD3 is to hydrolyze ester bonds in bioactive lipids, influencing the signaling pathways that regulate cellular functions. Knockout of the ABHD3 gene allows for the examination of the enzymatic activity's absence in vitro, shedding light on how its loss impacts cellular communication and metabolic processes. Researchers can use these knockout lines to model diseases associated with aberrant lipid signaling, providing insights into potential therapeutic targets for treatment.

The scientific importance of ABHD3 Gene Knockout Cell Lines extends to both basic research and clinical applications. In neuroscience, these models can help unravel the molecular mechanisms underlying neurodegenerative diseases, while in oncology, they hold promise for identifying lipid-related aberrations in cancer metabolism. Understanding the consequences of ABHD3 disruption paves the way for innovative treatment strategies and drug development.

What sets ABHD3 Gene Knockout Cell Lines apart from traditional cell culture methods is their specificity and precision. The targeted gene knockout mechanism minimizes off-target effects, providing a more reliable experimental design. Additionally, these lines can easily be characterized and validated, ensuring reproducibility in research outcomes.

For researchers and clinicians seeking to delve into the intricacies of lipid biology and its implications in health and disease, ABHD3 Gene Knockout Cell Lines represent an invaluable resource. They not only facilitate the exploration of novel research avenues but also enhance the potential to transform scientific findings into applicable therapies.

Our company specializes in providing high-quality biological products, including genetically modified cell lines tailored for advanced research. With a commitment to innovation and scientific excellence, we ensure that our offerings support impactful discoveries in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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