Gene: ABHD18
Official Full Name: abhydrolase domain containing 18provided by HGNC
Gene Summary: Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26170 | ABHD18 Knockout cell line (HeLa) | Human | ABHD18 | 1:3~1:6 | Negative | Online Inquiry |
KO26171 | ABHD18 Knockout cell line (HCT 116) | Human | ABHD18 | 1:2~1:4 | Negative | Online Inquiry |
KO26172 | ABHD18 Knockout cell line (HEK293) | Human | ABHD18 | 1:3~1:6 | Negative | Online Inquiry |
KO26173 | ABHD18 Knockout cell line (A549) | Human | ABHD18 | 1:3~1:4 | Negative | Online Inquiry |
ABHD18 Gene Knockout Cell Lines are a specialized tool designed to facilitate the study of the ABHD18 gene, which encodes a member of the alpha/beta hydrolase domain-containing protein family. These cell lines are engineered to harbor targeted deletions in the ABHD18 gene, enabling researchers to investigate the functional roles of this gene in various biological processes. By eliminating ABHD18 expression, these cell lines serve as a vital resource for assessing the impact of ABHD18 on lipid metabolism, neurobiology, and other cellular functions.
The primary mechanism by which ABHD18 Gene Knockout Cell Lines operate is through the abrogation of ABHD18 protein synthesis, leading to changes in enzymatic activity associated with lipid homeostasis. This alteration provides insight into the physiological and pathological roles of the enzyme, including its involvement in the metabolism of lipid signaling molecules. Thus, these cell lines are invaluable in elucidating the mechanisms underlying metabolic diseases and neurological disorders, offering implications for drug discovery and therapeutic interventions.
Scientifically, the ABHD18 Gene Knockout Cell Lines are crucial for advancing research in lipidomics, cell signaling, and broad-spectrum disease models. They are particularly beneficial for researchers investigating the contributions of lipid mediators in health and disease, allowing for high-throughput screening of potential pharmacological agents in relevant cellular contexts.
Compared to alternative gene knockout models, our ABHD18 Gene Knockout Cell Lines are characterized by their rigorous validation, consistent performance, and user-friendly protocols. This reliability reduces variability in experimental results, ultimately saving researchers valuable time and resources. Furthermore, the specificity of these cell lines ensures that researchers can confidently attribute observed phenotypes to the absence of ABHD18.
For researchers and clinicians, the value of ABHD18 Gene Knockout Cell Lines lies in their ability to deepen understanding of lipid regulatory networks and their potential therapeutic targets. By harnessing these advanced tools, users can explore uncharted territories in lipid biology and contribute to the foundational knowledge necessary for future innovations.
As a leading provider in precision cell line development, our company prides itself on delivering high-quality biological products backed by a commitment to scientific excellence and customer support. Our expertise ensures that researchers have access to the most reliable tools for their investigations.
Please note that all services are for research use only. Not intended for any clinical use.
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