Gene: ABCD4
Official Full Name: ATP binding cassette subfamily D member 4provided by HGNC
Gene Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in several protein-coding and non-protein-coding variants. [provided by RefSeq, Jul 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO35765 | ABCD4 Knockout cell line (HeLa) | Human | ABCD4 | 1:3~1:6 | Negative | Online Inquiry |
KO35766 | ABCD4 Knockout cell line (HCT 116) | Human | ABCD4 | 1:2~1:4 | Negative | Online Inquiry |
KO35767 | ABCD4 Knockout cell line (HEK293) | Human | ABCD4 | 1:3~1:6 | Negative | Online Inquiry |
KO35768 | ABCD4 Knockout cell line (A549) | Human | ABCD4 | 1:3~1:4 | Negative | Online Inquiry |
ABCD4 Gene Knockout Cell Lines are precisely engineered cellular models designed to facilitate the study of the ABCD4 gene's biological functions. These cell lines are generated through advanced CRISPR/Cas9 technology, which enables targeted disruption of the ABCD4 gene sequence. The knockout of this gene allows researchers to assess its role in various physiological and pathological processes, including cellular metabolism, signaling pathways, and disease mechanisms.
Functionally, ABCD4 Gene Knockout Cell Lines exhibit altered biological behaviors when compared to their wild-type counterparts. By completely abrogating the expression of the ABCD4 gene, researchers can observe downstream effects on cellular functions such as growth, differentiation, and response to stimuli. This comprehensive insight into gene function is vital for elucidating the underlying mechanisms of diseases, making these cell lines indispensable tools in molecular and cellular biology.
The scientific significance of ABCD4 Gene Knockout Cell Lines extends into both research and clinical realms. They can be employed in drug discovery, allowing for the identification of therapeutic targets and the assessment of drug efficacy in relevant cancer and metabolic models. Furthermore, these knockout lines are essential in translational research, where understanding gene function can inform patient-specific therapies and personalized medicine approaches.
What sets our ABCD4 Gene Knockout Cell Lines apart from alternatives on the market is their unparalleled specificity and reliability, enabled by stringent quality control during the cell line development process. Our established protocols demonstrate not only efficient gene knockout but also consistent phenotypic outcomes across multiple experiments, giving researchers confidence in their reproducibility.
For researchers and clinicians, the ability to utilize a validated knockout model accelerates the pace of discoveries and enhances the robustness of experimental results. Our commitment to providing high-quality biological products is backed by years of expertise in genomic technologies and a passionate focus on advancing scientific research. By choosing ABCD4 Gene Knockout Cell Lines, users gain access to a powerful resource that drives innovation in gene function studies.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.